181 Hiv Mutation

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Ask the Experts

The Y181C Mutation

Dear Drs. Is the Y181C mutation that showed up 7 years ago after taken viramune that does not appear on a genotype done today rule out sustiva as a drug option? Thank you....

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.In general resistance to one NNRTI [in your case, selected by nevirapine (Viramune) and evidenced by the Y181C mutation] confers resistance to other NNRTIs, like efavirenz (Sustiva). For this reason, if you've had previous... Read more »

Number of mutations

Welcome! I was wondering if anyone has ever quantified the number of possible mutations? Are there... Read more »

Response from Renslow Sherer, M.D. »

Mutation Test for Anti-HIV Drugs

I recently read (in The Washington Blade) a brief piece about a mutation test that "a... Read more »

Response from Cal Cohen, M.D., M.S. »

Go to Ask the Experts »

Articles

APOBEC3G/F Mutation Not Responsible for HIV Viremia Control in Most Elite HIV Suppressors

There's nothing like hearing the results of studies directly from those who actually conducted the research. It is these women and men who are transforming HIV treatment and care. In this interview, you'll meet one of these impressive HIV... Read more »

HIV Might Be Result of Gene Mutation, Study Says

HIV might be the result of a gene mutation that occurred when the simian immunodeficiency virus -- believed to be the progenitor of HIV -- jumped from apes to humans, according to a study published Thursday in the journal Cell , Reuters reports.... Read more »

Gene Mutation That Protects Against Virtually Extinct Form of Malaria Makes Blacks More Susceptible to HIV, Study Says

A gene mutation that likely protected people living in sub-Saharan Africa from a form of malaria seldom found in the region now could make blacks more susceptible to HIV, according to a study published Wednesday in the journal Cell Host &... Read more »

NNRTIs: The Next Generation Approaches

Part I Introduction Mechanisms of NNRTI Activity and HIV NNRTI Resistance NNRTI Resistance in NNRTI-Naive and NNRTI-Experienced Individuals NNRTI Mutations: Resistance and Cross-Resistance NRTI Mutations: The Potential Impact on NNRTIs NNRTI... Read more »

Connect With Others

mutated hiv

Posted by Anonymous, 1 Reply

Recently Is that true the fact that exist mutated hiv(can't detect Antibody test)?
If the fact's true.. How should we do?

Read more »

mutation

Posted by drnsee, 3 Replies

I'm aware that the HIV virus itself may mutate over time. However, my partner who has had HIV twice as long as I have heard that it actually mutates your own [human] DNA. That it integrates into your system so much that this happens over time.

I'm... Read more »

Mutation?

Posted by Anonymous, 2 Replies

Is it possible to have an undetectable or mutated hiv strain? Possible exposure 8 years ago, -ve elisa and DNA PCR taken in the past 4 months. Tons of symptoms within the last year or so.... candida interigo rash, HPV oral warts, proximal toe nail... Read more »

HIV1?HIV2?HIV-O?HIV-N?

Posted by Anonymous, 1 Reply

We didn't even know about HIV until the 1980's. So, we invented a HIV1 test, only to find there is a HIV2. So, we invented a HIV2 only to find out there is a HIV-O. Why are we so ignorant to think there couldn't be another strain...for which we... Read more »

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