• Swedish Medical Center HIV Research Studies
• Research Study at UW Medical Center on Women Living With HIV

Swedish Medical Center HIV Research Studies

1. Research Study for HIV+ Persons Failing Their Current Regimen

   48-week study of an experimental NNRTI in combination with other antiretroviral drugs in people who have resistance to protease inhibitors and NNRTIs.

   To qualify you must have:

   • HIV Viral Load > 1,000 copies/mL
   • Documented resistance testing showing resistance to PIs and NNRTIs

   Please contact Heather 206-386-2820 for more information.

2. HIV Study for Multiply-Treated People Who Are Failing Their Current Regimen

   48-week study of an investigational protease inhibitor with a combination of other drugs.

   Study related lab tests, including genotyping and physical exams are free. The investigational drug is provided at no cost.

   Reimbursement for childcare and transportation are possible. Will work around your schedule (evenings, weekends, etc.)

   Please contact Janice at 206-386-2523 for more information.

   Tipranavir Early Access Program

   A limited number of spaces in the Tipranavir early access program are available to persons with private providers and through the Madison Clinic. Patients must have a CD4 count <100 copies/mm³.

   Please contact Heather at 206-386-2820 for more information.

3. Protease Inhibitor Switch Study

   48-week research study of HIV+ people that will replace Kaletra® with a currently-marketed protease inhibitor to see if it will improve cholesterol levels. To take part in this study, your current viral load must be <50 copies/mL. This trial includes:

   • Laboratory testing
   • Physical Exams
   • Some Medications
   • Reimbursement for travel and child care.

   Please contact Heather at 206-386-2820 for more information.

Research Study at UW Medical Center on Women Living With HIV

Factors That Affect Genital HIV-1 Shedding in Women

Study Overview

Little is known about how HIV affects women as compared to men. The purpose of this study is to find what factors affect the amount of HIV present in the vagina and cervix and how this may differ from the amount of HIV present in the blood. We think that hormones, and vaginal and cervical infections may influence how HIV acts in the vagina and cervix. This is important because an increase in HIV in the vagina or cervix could lead to changes in HIV in the rest of a woman's body.

Eligibility

HIV positive women ages 14-49 years
Non-pregnant or not postmenopausal women
Ability to keep study appointments

Study Requirements

Four study visits in the first year and three visits per year in the following 4 years. Each visit will last approximately one hour and include:

• Questionnaire
• Blood sample (viral load)
• Urine sample
• Pelvic exam
• Speculum exam
• Cervical biopsy

We will ask you to collect samples from your mouth and vagina. These collections are done daily for 2 months at a time, 3 times in the first study year (a total of 6 months).

Medical examinations and lab tests are provided at no cost.

Reimbursement

You will receive $25 for each study visit and $25 per month of daily home samples. If all of the scheduled visits and daily home samples are completed, you will be compensated a total of $250 during the first year and $75 per year for the following years.

Contact

We appreciate your interest in this study. Please call us for further information: Women's Health Care Research: 206-543-5557 (please ask for Jan or Jenni)