BusinessWeek in its Oct. 1 edition profiled researchers at Microsoft who are refocusing spam-blocking technology to locate HIV-infected cells to help produce vaccines. Researchers have reconfigured the technology originally developed to identify junk e-mail to correlate HIV-infected cell mutations with an individual's genetic profile.
According to BusinessWeek, David Heckerman and colleagues in June released their first set of detecting software on the Internet at no cost. The researchers run data through 320 computers at a rate that is 480 times faster than one year ago due to smarter algorithms and more powerful machines. Heckerman said he hopes within three years the technology will lead to vaccines that can be tested on humans.
One of the challenges for the researchers is to single out the combinations of protein that lead to an HIV-infected cell so the protein bits can be packaged into a vaccine, BusinessWeek reports. In addition, Heckerman said HIV-infected mutations appear to vary according to an individual's immune system. If researchers can find patterns, it could bolster development of an effective vaccine (Baker/Greene, BusinessWeek, 10/1).
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Reprinted with permission from kaisernetwork.org. You can view the entire Kaiser Daily HIV/AIDS Report, search the archives, or sign up for email delivery at www.kaisernetwork.org/dailyreports/hiv. The Kaiser Daily HIV/AIDS Report is published for kaisernetwork.org, a free service of the Kaiser Family Foundation, by The Advisory Board Company. © 2007 by The Advisory Board Company and Kaiser Family Foundation. All rights reserved.
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