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Research Report Series

Anabolic Steroid Abuse

April 2000

Where Can I Get Further Scientific Information About Steroid Abuse?

NIDA Web Sites
www.drugabuse.gov
www.steroidabuse.org

NCADI
Web Site: www.health.org
Phone: 1-800-729-6686

Fact sheets on anabolic steroids, other illicit drugs, and related topics can be ordered free, in English and Spanish, by calling NIDA Infofax at 1-888-NIH-NIDA (1-888-644-6432) or, for those with hearing impairment, 1-888-TTY-NIDA (1-888-889-6432).

Information on steroid abuse also can be accessed through the NIDA Steroid Abuse Web Site (www.steroidabuse.org/). Information on illicit drugs in general can be accessed through NIDA's home page (www.drugabuse.gov/) or by contacting the National Clearinghouse for Alcohol and Drug Information (NCADI) Web Site (www.health.org/).


Glossary

Addiction

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: A chronic, relapsing disease, characterized by compulsive drug-seeking and use and by neurochemical and molecular changes in the brain.

Anabolic effects: Drug-induced growth or thickening of the body's nonreproductive tract tissues -- including skeletal muscle, bones, the larynx, and vocal cords -- and decrease in body fat.

Analgesics: A group of medications that reduce pain.

Androgenic effects: A drug's effects upon the growth of the male reproductive tract and the development of male secondary sexual characteristics.

Antidepressants: A group of drugs used in treating depressive disorders.

Cardiovascular system: The heart and blood vessels.

Hormone: A chemical substance formed in glands in the body and carried in the blood to organs and tissues, where it influences function, structure, and behavior.

Musculoskeletal system: The muscles, bones, tendons, and ligaments.

Placebo: An inactive substance, used in experiments to distinguish between actual drug effects and effects that are expected by the volunteers in the experiments.

Sex hormones: Hormones that are found in higher quantities in one sex than in the other. Male sex hormones are the androgens, which include testosterone; and the female sex hormones are the estrogens and progesterone.

Withdrawal: Symptoms that occur after chronic use of a drug is reduced or stopped.


References

Bahrke, M.S., Yesalis, C.E., and Wright, J.E. Psychological and behavioral effects of endogenous testosterone and anabolic-androgenic steroids: an update. Sports Medicine 22(6): 367-390, 1996.

Blue, J.G., and Lombardo, J.A. Steroids and steroid-like compounds. Clinics in Sports Medicine 18(3): 667-689, 1999.

Bronson, F.H., and Matherne, C.M. Exposure to anabolic-androgenic steroids shortens life span of male mice. Medicine and Science in Sports and Exercise 29(5): 615-619, 1997.

Brower, K.J. Withdrawal from anabolic steroids. Current Therapy in Endocrinology and Metabolism 6: 338-343, 1997.

Elliot, D., and Goldberg, L. Intervention and prevention of steroid use in adolescents. The American Journal of Sports Medicine 24(6): S46-S47, 1996.

Goldberg, L., et al. Anabolic steroid education and adolescents: Do scare tactics work? Pediatrics 87(3): 283-286, 1991.

Goldberg, L., et al. Effects of a multidimensional anabolic steroid prevention intervention: The Adolescents Training and Learning to Avoid Steroids (ATLAS) Program. Journal of the American Medical Association 276(19): 1555-1562, 1996.

Goldberg, L., et al. The ATLAS program: Preventing drug use and promoting health behaviors. Archives of Pediatrics and Adolescent Medicine 154: 332-338, 2000.

Gruber, A.J., and Pope, H.G., Jr. Compulsive weight lifting and anabolic drug abuse among women rape victims. Comprehensive Psychiatry 40(4): 273-277, 1999.

Gruber, A.J., and Pope, H.G., Jr. Psychiatric and medical effects of anabolic-androgenic steroid use in women. Psychotherapy and Psychosomatics 69: 19-26, 2000.

Hoberman, J.M., and Yesalis, C.E. The history of synthetic testosterone. Scientific American 272(2): 76-81, 1995.

Leder, B.Z., et al. Oral androstenedione administration and serum testosterone concentrations in young men. Journal of the American Medical Association 283(6): 779-782, 2000.

The Medical Letter on Drugs and Therapeutics. Creatine and androstenedione -- two "dietary supplements." 40(1039): 105-106, 1998.

Middleman, A.B, et al. High-risk behaviors among high school students in Massachusetts who use anabolic steroids. Pediatrics 96(2): 268-272, 1995.

Pope, H.G., Jr., Kouri, E.M., and Hudson, M.D. Effects of supraphysiologic doses of testosterone on mood and aggression in normal men. Archives of General Psychiatry 57(2): 133-140, 2000.

Porcerelli, J.H., and Sandler, B.A. Anabolic-androgenic steroid abuse and psychopathology. Psychiatric Clinics of North America 21(4): 829-833, 1998.

Porcerelli, J.H., and Sandler, B.A. Narcissism and empathy in steroid users. American Journal of Psychiatry 152(11): 1672-1674, 1995.

Rich, J.D., Dickinson, B.P., Flanigan, T.P., and Valone, S.E. Abscess related to anabolic-androgenic steroid injection. Medicine and Science in Sports and Exercise 31(2): 207-209, 1999.

Su, T.-P., et al. Neuropsychiatric effects of anabolic steroids in male normal volunteers. Journal of the American Medical Association 269(21): 2760-2764, 1993.

Sullivan, M.L., Martinez, C.M., Gennis, P., and Gallagher, E.J. The cardiac toxicity of anabolic steroids. Progress in Cardiovascular Diseases 41(1): 1-15, 1998.

Yesalis, C.E. Anabolic Steroids in Sports and Exercise, 2nd edition. Champaign, IL: Human Kinetics. In press.

Yesalis, C.E. Androstenedione. Sport Dietary Supplements Update, 2000, E-SportMed.com.

Yesalis, C.E. Trends in anabolic-androgenic steroid use among adolescents. Archives of Pediatrics and Adolescent Medicine 151: 1197-1206, 1997.

Yesalis, C.E., Kennedy, N.J., Kopstein, A.N., and Bahrke, M.S. Anabolic-androgenic steroid use in the United States. Journal of the American Medical Association 270(10): 1217-1221, 1993.

Zorpette, G. Andro angst. Scientific American 279(6): 22-26, 1998.


  
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This article was provided by U.S. National Institute on Drug Abuse.
 

 

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