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Nelfinavir Interaction With Warfarin

March/April 2011

On 24 February 2011, FDA updated the nelfinavir (Viracept) label to include drug-drug interaction information between nelfinavir and wafarin.

Table 11 (Established and Other Potentially Significant Drug Interactions) of the Precautions section of the label was changed to add the following:

Coadministration of wafarin and nelfinavir may affect concentrations of wafarin. It is recommended that the INR (international normalised ratio) be monitored carefully during treatment with nelfinavir, especially when commencing therapy.

Please refer to the full label for details.

www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

Source: FDA list serve (24 Feb 2011).


Reference

Viracept (nelfinavir) Label change reflects drug-drug interaction information with warfarin
www.fda.gov/ForConsumers/ByAudience/ForPatientAdvocates/HIVandAIDSActivities/ucm244619.htm

Links to external websites are current at time of posting but not maintained.



  
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This article was provided by HIV i-Base. It is a part of the publication HIV Treatment Bulletin. Visit HIV i-Base's website to find out more about their activities, publications and services.
 
See Also
More on HIV Medications
More News on Nelfinavir (Viracept)

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