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Stopping PCP Prevention Is Possible at Lower CD4s

February 2011

In September 2010, study results from the European COHERE study were published showing that some people could stop taking preventive treatment for PCP (Pneumocystis jiroveci pneumonia) provided that their viral loads were under control by a potent HIV regimen. Earlier in the epidemic, PCP quickly became an AIDS-defining illness and a leading cause of death for people living with HIV. It most often appeared when CD4 counts fell below 200.

In response, PCP preventive treatment (usually Bactrim) was recommended for anyone with CD4s in this range and certain others whose health warranted it. Many new cases of PCP were avoided because of this new standard of care, but also because of many improvements HIV therapy over the years. Taking Bactrim can be an added burden for some, so being able to stop it safely would be welcome news.

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See Also
How to Prevent PCP
More on Pneumocystis Pneumonia (PCP) Treatment

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