Global Campaign for Microbicides Lauds Milestone in HIV Prevention Findings That Daily Use of Anti-Retroviral Protects Against HIV Infection
November 23, 2010
Johannesburg, South Africa and Washington, D.C. -- The Global Campaign for Microbicides (GCM) welcomes today's news from the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Disease (NIAID) of the US National Institutes of Health (NIH) and the Gladstone Institutes of the University of California, San Francisco that daily use of oral emtricitabine (FTC) with tenofovir (TDF) in one tablet shows promise to safely and effectively help to prevent HIV infection among men who have sex with men (MSM).
The iPrEx Study, conducted in six countries spanning four continents, found an average of 43.8 percent fewer HIV infections among individuals at high risk for infection who took a FTC/TDF tablet compared to those given a placebo tablet. FTC/TDF is already being used to treat people living with HIV infection.
"This has been a landmark year for HIV prevention research," said Yasmin Halima, director of the Global Campaign for Microbicides. "We now have proof of concept that both topical gels and oral pills have potential to work in preventing HIV among those at highest risk."
While the trial did not study the effectiveness of FTC/TDF in women, it gives the Global Campaign and scientific community reason to be optimistic about its potential. Women around the world continue to bear the greatest burden of HIV and findings from other PrEP trials that are currently underway, such as VOICE, will be an important milestone in demonstrating success and the move toward licensure of both the gel and oral pills for women who are most at risk.
Given the Global Campaign's mission to ensure access to new and existing HIV prevention options, especially for women, 2013 -- the year that results of the VOICE trial are due -- may prove to be an even more exciting year. The Global Campaign has been advocating for and supporting the critical need for more HIV prevention methods for nearly 12 years.
"There is light at the end of the long HIV prevention research tunnel," continued Halima. "With good news on the product front, efforts must be stepped up to ensure that the drug is approved and political and community will is established for such products to get in the hands of people who need them as quickly as possible."
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