South Africa: Comparative Effectiveness of HIV Testing and Treatment in Highly Endemic Regions
November 2, 2010
"Universal testing and treatment holds promise for reducing the burden of [HIV] in sub-Saharan Africa, but linkage from testing to treatment sites and retention in care are inadequate," according to the study's introduction.
The researchers developed an HIV epidemic and disease progression simulation in South Africa to compare the outcomes of the present HIV treatment campaign (status quo) with four HIV testing and treatment strategies that increase access to antiretroviral therapy: (1) universal testing and treatment absent changes in linkage to care and loss to follow-up; (2) universal testing and treatment with enhanced linkage to care; (3) universal testing and treatment with reduced loss to follow-up; and (4) comprehensive HIV care with universal testing and treatment, improved linkage to care and reduced loss the follow-up. Survival benefits, new HIV infections, and HIV prevalence were the main outcome measures.
Archives of Internal Medicine
08.09.2010; Vol. 170; No. 15: P. 1347-1354; Eran Bendavid, MD, MS; Margaret L. Brandeau, PhD; Robin Wood, MD; Douglas K. Owens, MD, MS
This article was provided by CDC National Prevention Information Network. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update.
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