Print this page    •   Back to Web version of article

HIV Drug Chart/Overview

May 2012

Table of Contents


Introduction

The number of drugs available to fight HIV keeps growing. This is good news, but it can also make it difficult to figure out what's what. Use this HIV drugs overview to find basic information on all of the Food and Drug Administration (FDA)-approved HIV drugs, such as:

We have also listed the drug makers and their internet addresses so you can get more information about each drug and patient assistance. Most companies have a patient or prescription assistance program (PAP) to help you get a drug if you have no insurance and can't afford it. Some companies offer help with co-payments for those who do have insurance.


Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Emtriva

Brand Name: Emtriva
Other Name(s):FTC
Generic Name(s):Emtricitabine
Class of Drug:NRTI
Common Side Effects:Nausea, diarrhea, headaches, rash, skin discoloration
Serious Side Effects:Lactic acidosis, liver problems, lipodystrophy
Special Considerations:Get tested for hepatitis B (HBV) before taking Emtriva. Emtriva fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Emtriva may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs
Who Produces the Drug:Gilead
Web Site for Drug Info:www.gileadhiv.com
Patient Assistance:Gilead Patient Assistance
1-800-226-2056
Co-payment assistance at 1-888-358-0398


Epivir

Brand Name: Epivir
Other Name(s):3TC
Generic Name(s):Lamivudine
Class of Drug:NRTI
Common Side Effects:Nausea, diarrhea, headaches, fatigue
Serious Side Effects:Liver problems, lipodystrophy, peripheral neuropathy, pancreatitis
Special Considerations:Get tested for hepatitis B (HBV) before taking Epivir. Epivir fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Epivir may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects; short-term use demonstrated to be safe for mothers and infants; present in breast milk of nursing mothers
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Epivir
Patient Assistance:Bridges to Access
1-866-728-4368
Co-payment assistance at www.mysupportcard.com/
Viiv Healthcare Patient Assistance Program
877-784-4842


Retrovir

Brand Name: Retrovir
Other Name(s):AZT, ZDV
Generic Name(s):Zidovudine
Class of Drug:NRTI
Common Side Effects:Nausea, vomiting, loss of appetite, headaches, fatigue, trouble sleeping
Serious Side Effects:Anemia, neutropenia, Lactic acidosis, liver problems, lipodystrophy, myopathy (muscle pain and weakness)
Pregnancy:No evidence of increased likelihood of birth defects; short-term use demonstrated to be safe for mothers and infants; effective at reducing mother-to-child transmission
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs, especially Retrovir
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Retrovir
Patient Assistance:Bridges to Access
1-866-728-4368
Co-payment assistance at http://www.mysupportcard.com/
Viiv Healthcare Patient Assistance Program
877-784-4842


Videx EC

Brand Name: Videx EC
Other Name(s):ddI
Generic Name(s):Didanosine
Class of Drug:NRTI
Common Side Effects:Nausea, diarrhea, headaches, trouble sleeping, rash
Serious Side Effects:Peripheral neuropathy, pancreatitis, Lactic acidosis, liver problems, lipodystrophy; rarely, a severe liver condition known as non-cirrhotic portal hypertension that can be fatal
Special Considerations:Methadone, a drug often used by those recovering from heroin addiction, can reduce the amount of Videx in the blood and make Videx less effective
Pregnancy:Sometimes fatal lactic acidosis in pregnant women taking Videx and Zerit together
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs, especially Videx
Who Produces the Drug:Bristol-Myers Squibb
Web Site for Drug Info:Videx EC
Patient Assistance:

The Partnership for Prescription Assistance
1-888-477-2669 or www.pparx.org
No co-payment assistance is available


Viread

Brand Name: Viread
Other Name(s):TDF
Generic Name(s):Tenofovir
Class of Drug:NRTI
Common Side Effects:Nausea, vomiting, loss of appetite, diarrhea, gas, rash, headache, weakness
Serious Side Effects:Kidney problems, bone problems, Lactic acidosis, liver problems, lipodystrophy
Special Considerations:Get tested for hepatitis B (HBV) before taking Viread. Viread fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Viread may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs
Who Produces the Drug:Gilead
Web Site for Drug Info:Viread
Patient Assistance:Gilead Patient Assistance
1-800-226-2056
Co-payment assistance at 1-888-358-0398


Zerit

Brand Name: Zerit
Other Name(s):d4T
Generic Name(s):Stavudine
Class of Drug:NRTI
Common Side Effects:Nausea, vomiting, diarrhea, headaches, fatigue, rash
Serious Side Effects:peripheral neuropathy, pancreatitis, Lactic acidosis, liver problems, lipodystrophy
Special Considerations:Methadone, a drug often used by those recovering from heroin addiction, can reduce the amount of Zerit in the blood and make Zerit less effective
Pregnancy:Sometimes fatal lactic acidosis in pregnant women taking Videx and Zerit together
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs, especially Zerit
Who Produces the Drug:Bristol-Myers Squibb
Web Site for Drug Info:Zerit
Patient Assistance:

The Partnership for Prescription Assistance
1-888-477-2669 or www.pparx.org
No co-payment assistance is available


Ziagen

Brand Name: Ziagen
Other Name(s):ABC
Generic Name(s):Abacavir
Class of Drug:NRTI
Common Side Effects:Nausea, vomiting, headache, fatigue, loss of appetite, trouble sleeping
Serious Side Effects:Hypersensitivity reaction, Lactic acidosis, liver problems, lipodystrophy
Special Considerations:HLA-B*5701 screening (for hypersensitivity reaction) is recommended before starting a Ziagen-containing regimen. Studies do not agree on whether taking Ziagen can increase your risk of heart disease. If you think you might be at increased risk of heart disease, you should talk to your health care provider about whether you should take Ziagen.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Ziagen
Patient Assistance:Bridges to Access
1-866-728-4368
Co-payment assistance at www.mysupportcard.com/
Viiv Healthcare Patient Assistance Program
877-784-4842


Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

Edurant

Brand Name: Edurant
Other Name(s):RPV
Generic Name(s):Rilpivirine
Class of Drug:NNRTI
Common Side Effects:Rash, headache, trouble sleeping, depression, anxiety, dizziness, muscle aches
Serious Side Effects:Liver problems, lipodystrophy, severe depression and suicidal thoughts
Special Considerations:Only approved for people starting HIV treatment for the first time
Pregnancy:No information in human pregnancy
Who Produces the Drug:Tibotec
Web Site for Drug Info:www.edurant-info.com/
Patient Assistance:Johnson and Johnson Patient Assistance Foundation: www.jjpaf.org or 800-652-6227
Tibotec Patient Savings Program (for help with co-pays): 866-961-7169


Intelence

Brand Name: Intelence
Other Name(s):ETR
Generic Name(s):Etravirine
Class of Drug:NNRTI
Common Side Effects:Nausea, rash, diarrhea, peripheral neuropathy, headache, high blood pressure
Serious Side Effects:Hypersensitivity (rash, flu-like symptoms, and sometimes organ problems, including liver failure), Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Contact your health care provider immediately if symptoms of severe skin reactions develop
Pregnancy:No information in human pregnancy
Women-Specific Information:Women are more likely to experience nausea than men when taking Intelence
Who Produces the Drug:Tibotec
Web Site for Drug Info:www.intelence-info.com
Patient Assistance:Intelence Patient Assistance Program
800-652-6227
Tibotec Patient Savings Program (for help with co-pays): 866-961-7169


Rescriptor

Brand Name: Rescriptor
Other Name(s):DLV
Generic Name(s):Delavirdine
Class of Drug:NNRTI
Common Side Effects:Nausea, diarrhea, headaches, fatigue, rash, fever
Serious Side Effects:Stevens Johnson Syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling), liver problems (may include yellowing of the skin and eyes)
Special Considerations:People with low amounts of acid in their stomach (achlorhydria) should take Rescriptor with a liquid that contains some acid, like orange or cranberry juice
Pregnancy:No information in human pregnancy
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Rescriptor
Patient Assistance:Bridges to Access
866-728-4368
Viiv Healthcare Patient Assistance Program
877-784-4842
Co-payment assistance at www.mysupportcard.com/


Sustiva

Brand Name: Sustiva (or Stocrin outside the US)
Other Name(s):EFV
Generic Name(s):Efavirenz
Class of Drug:NNRTI
Common Side Effects:Nausea, diarrhea, headaches, fatigue, rash, trouble sleeping, confusion, drowsiness, abnormal dreams
Serious Side Effects:Severe mood changes (including anxiety, depression, suicidal thoughts, aggression), Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling), liver problems, lipodystrophy
Special Considerations:Women who are pregnant or may get pregnant should not use Sustiva-containing regimens
Pregnancy:There is evidence of an increased risk of birth defects in babies born to women who use Sustiva during pregnancy
Women-Specific Information:Because Sustiva reduces the levels of some hormonal contraceptives, talk to your health care provider about adding a reliable barrier method of contraception if you take Sustiva
Who Produces the Drug:Bristol-Myers Squibb
Web Site for Drug Info:www.sustiva.com
Patient Assistance:Sustiva Patient Assistance or 1-888-281-8981
Co-payment assistance at www.bmshivcopayprogram.com/


Viramune

Brand Name: Viramune
Other Name(s):NVP
Generic Name(s):Nevirapine
Class of Drug:NNRTI
Common Side Effects:Rash, nausea, headaches, fever, fatigue
Serious Side Effects:Liver damage, lipodystrophy, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Women with CD4 cell counts greater than 250 (including pregnant women) and men with CD4 cell counts above 400 at the time of starting treatment have a higher risk of serious liver damage. Careful dosing and liver monitoring is needed when starting Viramune.
Pregnancy:No evidence of increased likelihood of birth defects. Evidence suggests that taking a drug regimen including Viramune while pregnant reduces mother-to-child transmission of HIV. Viramune is present in breast milk.
Women-Specific Information:Because Viramune reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Viramune. Women taking Viramune are more likely than men to develop rash, and may also be more likely to develop liver damage.
Who Produces the Drug:Boehringer-Ingelheim
Web Site for Drug Info:www.viramune.com
Patient Assistance:Viramune Patient Assistance or 1-800-556-8317
Co-payment assistance -- speak to your health care provider about obtaining a Viramune Co-Pay Savings Card


Integrase Inhibitors

Isentress

Brand Name: Isentress
Other Name(s):RGV
Generic Name(s):Raltegravir
Class of Drug:Integrase inhibitors
Common Side Effects:diarrhea, nausea, headaches, trouble sleeping
Serious Side Effects:Liver toxicity, elevated levels of a muscle enzyme called creatine kinase
Special Considerations:Should be used with caution by people who are at increased risk for muscle problems like myopathy and rhabdomyolysis. Contact your health care provider if you experience unexplained muscle pain, tenderness, or weakness.
Pregnancy:No information in human pregnancy
Women-Specific Information:A recent study conducted by Merck showed Isentress to be safe and effective in women and blacks
Who Produces the Drug:Merck
Web Site for Drug Info:www.isentress.com
Patient Assistance:Merck Patient Assistance Program
1-800-850-3430
Co-payment assistance


Protease Inhibitors (PIs)

Aptivus

Brand Name: Aptivus
Other Name(s):TPV
Generic Name(s):Tipranavir
Class of Drug:PI
Common Side Effects:Nausea, vomiting, diarrhea, stomach pain, fatigue, headaches
Serious Side Effects:Liver problems, lipodystrophy, increased cholesterol and triglycerides, sulfa allergy, high blood sugar, internal bleeding, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Should not be taken by people with moderate-to-severe hepatitis B or C
Pregnancy:No information in human pregnancy
Women-Specific Information:Because Aptivus reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Aptivus. Skin rash is a more common side effect in women taking birth control pills or hormone replacement therapy.
Who Produces the Drug:Boehringer Ingelheim
Web Site for Drug Info:www.aptivus.com
Patient Assistance:Aptivus Patient Assistance Program or 1-800-556-8317
No co-payment assistance is available

Crixivan

Brand Name: Crixivan
Other Name(s):IDV
Generic Name(s):Indinavir
Class of Drug:PI
Common Side Effects:Nausea, vomiting, diarrhea, stomach pain, heartburn, headaches, fatigue, trouble sleeping, rash, dry or itchy skin, hair loss, back pain
Serious Side Effects:Kidney stones (drink 8 glasses of water daily to lower risk of kidney stones), hemolytic Anemia (destruction of red blood cells), lipodystrophy, increased cholesterol and triglycerides, high blood sugar, jaundice (yellowing of the skin and eyes), increased bleeding in people with hemophilia
Special Considerations:Do not take Crixivan with grapefruit juice
Pregnancy:No evidence of increased birth defects. There is some concern about Crixivan's effect on infant liver health. Use of Crixivan without Norvir during pregnancy is not recommended.
Women-Specific Information:Some studies suggest that women taking Crixivan are more likely than men to develop kidney problems
Who Produces the Drug:Merck
Web Site for Drug Info:Crixivan
Patient Assistance:Reimbursement Support Program
1-800-850-3430
No co-payment assistance is available

Invirase

Brand Name: Invirase
Other Name(s):SQV
Generic Name(s):Saquinavir
Class of Drug:PI
Common Side Effects:Nausea, diarrhea, stomach pain, gas, headaches, fatigue, trouble sleeping, mental confusion
Serious Side Effects:lipodystrophy, high blood sugar, increased cholesterol and triglycerides, increased bleeding in people with hemophilia, jaundice (yellowing of the skin and eyes), increased risk of developing abnormal heart rhythms
Special Considerations:Another version of this drug called Fortovase was discontinued in the US in 2006, but is still used in other countries. Invirase is the only version available in the US.
Pregnancy:No evidence of increased birth defects. Evidence shows that Invirase + Norvir is safe in the short-term for mothers and infants.
Women-Specific Information:Because Invirase reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Inverase
Who Produces the Drug:Genentech (Roche)
Web Site for Drug Info: Invirase
Patient Assistance: Genentech's patient assistance program: RxAssist
1-877-757-6243
No co-payment assistance available


Kaletra

Brand Name: Kaletra (Aluvia in some countries outside the US)
Other Name(s):LPV/r
Generic Name(s):Lopinavir plus ritonavir (combined in the same tablet)
Class of Drug:PI
Common Side Effects:Nausea, vomiting, diarrhea, stomach pain, headaches, fatigue, weakness, heartburn
Serious Side Effects:Liver problems, pancreatitis, lipodystrophy, increased cholesterol and triglycerides, high blood sugar, increased bleeding in people with hemophilia
Pregnancy:No evidence of increased birth defects. Evidence shows that Kaletra is safe in the short-term for mothers and infants.
Women-Specific Information:Because Kaletra reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Kaletra
Who Produces the Drug:Abbott
Web Site for Drug Info: Kaletra
Patient Assistance: Kaletra Patient Assistance
1-800-222-6885
Abbott Patient Assistance Program
Co-payment assistance -- speak to your health care provider about obtaining an Abbott Positive Partnership PLUS Card or call 1-888-458-6442

Lexiva

Brand Name: Lexiva (Telzir in some countries outside the US)
Other Name(s):FPV
Generic Name(s):Fosamprenavir
Class of Drug:PI
Common Side Effects:Nausea, vomiting, diarrhea, stomach pain, gas, headaches, rash, numbness or tingling around the mouth
Serious Side Effects:Kidney stones (drink 8 glasses of water daily to lower risk of kidney stones), lipodystrophy, increased cholesterol and triglycerides, liver problems, sulfa allergy, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling), increased bleeding in people with hemophilia, high blood sugar, hemolytic Anemia (destruction of red blood cells)
Special Considerations:Triglyceride and cholesterol levels should be checked before starting Lexiva and regularly during treatment. It may be necessary for your health care provider to treat high cholesterol and triglycerides with other medications.
Pregnancy:No information in human pregnancy
Women-Specific Information:Because Lexiva reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Lexiva
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:www.lexiva.com
Patient Assistance:Lexiva Patient Assistance
Co-payment assistance at www.mysupportcard.com/
1-866-728-4368

Norvir

Brand Name: Norvir
Other Name(s):RTV
Generic Name(s):Ritonavir
Class of Drug:PI
Common Side Effects:Nausea, diarrhea, stomach pain, loss of appetite, headaches, heartburn, fatigue, weakness, dizziness, trouble sleeping, numbness and tingling around the mouth, changes in taste
Serious Side Effects:Liver problems, pancreatitis, lipodystrophy, increased cholesterol and triglycerides, high blood sugar, increased bleeding in people with hemophilia, increased risk of developing abnormal heart rhythms
Special Considerations:Norvir is most commonly used to boost other drugs. Taking Norvir with certain allergy medications, sedatives, heart medications, and migraine medications can increase the risk of their side effects.
Pregnancy:No evidence of increased likelihood of birth defects; use only to boost other HIV drugs
Women-Specific Information:Some research suggests that women may be more likely than men to experience side effects when taking Norvir, especially nausea, vomiting, aches and fatigue, and numbness and tingling around the mouth
Who Produces the Drug:Abbott
Web Site for Drug Info: Norvir
Patient Assistance: Norvir Patient Assistance Program
1-800-222-6885
Co-payment assistance program at 800-441-4987


Prezista

Brand Name: Prezista
Other Name(s):DRV
Generic Name(s):Darunavir
Class of Drug:PI
Common Side Effects:Nausea, vomiting, diarrhea, constipation, headaches, rash
Serious Side Effects:Liver problems, lipodystrophy, increased cholesterol and triglycerides, sulfa allergy, high blood sugar, increased bleeding in people with hemophilia, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Liver function should be tested before starting Prezista. Increased liver function monitoring is a good idea for people with hepatitis or other liver problems. Prezista is not recommended for people with severe liver damage.
Pregnancy:No information in human pregnancy
Women-Specific Information:Because Prezista reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Prezista
Who Produces the Drug:Janssen (formerly Tibotec)
Web Site for Drug Info:www.prezista.com
Patient Assistance: Prezista Patient Assistance Program
866-836-0114
Tibotec copay assistance: 866-961-7169


Reyataz

Brand Name: Reyataz
Other Name(s):ATV
Generic Name(s):Atazanavir
Class of Drug:PI
Common Side Effects:Nausea, vomiting, diarrhea, stomach pain, headaches, rash, jaundice (yellowing of skin and eyes), trouble sleeping, depression, dizziness, muscle aches, fever
Serious Side Effects:Liver problems, lipodystrophy, increased cholesterol and triglycerides, changes in heart rhythm, peripheral neuropathy, kidney stones, increased bleeding in people with hemophilia, gallbladder problems, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Pregnancy:No evidence of increased birth defects. There is some concern about Reyataz's effect on infant liver health.
Women-Specific Information:Because Reyataz reduces the levels of some hormonal contraceptives, talk to your health care provider about the right birth control pill for you
Who Produces the Drug:Bristol-Myers Squibb
Web Site for Drug Info:www.reyataz.com
Patient Assistance:Patient assistance or 888-281-8981
Co-payment assistance


Viracept

Brand Name: Viracept
Other Name(s):NFV
Generic Name(s):Nelfinavir
Class of Drug:PI
Common Side Effects:Nausea, diarrhea, gas, rash
Serious Side Effects:Liver problems, lipodystrophy, increased cholesterol and triglycerides, high blood sugar, increased bleeding in people with hemophilia
Pregnancy:No evidence of increased birth defects. Evidence shows that Viracept is safe in the short-term for mothers and infants.
Women-Specific Information:Because Viracept reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Viracept. Research suggests that women taking Viracept are less likely than men to experience diarrhea, but more likely to experience stomach pain, itching, or rash.
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info: Viracept
Patient Assistance:Viracept patient assistance program or
877-784-4842
Co-payment assistance


Entry and Fusion Inhibitors

Fusion Inhibitors

Fuzeon

Brand Name: Fuzeon
Other Name(s):T-20
Generic Name(s):Enfuvirtide
Class of Drug:Fusion Inhibitor
Common Side Effects:Skin reactions at site of shots (including pain and discomfort, redness, bumps, itching, swelling, and hardened skin), trouble sleeping, headaches, loss of appetite, depression, fatigue, muscle pain, constipation
Serious Side Effects:Increased risk for bacterial pneumonia, peripheral neuropathy, pancreas problems, possible rare allergic reaction (including rash, fever, nausea and vomiting, chills, shaking, low blood pressure, and increased liver enzymes)
Pregnancy:No information in human pregnancy
Who Produces the Drug:Trimeris/Roche; sold by Genentech
Web Site for Drug Info:www.fuzeon.com
Patient Assistance:Fuzeon patient assistance
1-877-438-9366
No co-payment assistance available


Entry Inhibitors

Selzentry

Brand Name: Selzentry (Celsentri outside the US)
Other Name(s):MVC
Generic Name(s):Maraviroc
Class of Drug:Entry Inhibitor
Common Side Effects:Cough, fever, colds, rash, muscle and joint pain, stomach pain, dizziness
Serious Side Effects:Liver problems, cardiovascular problems, feeling dizzy or blacking out when standing
Special Considerations:A laboratory test called a "tropism" test is needed before Selzentry is used to determine if treatment with the drug will be useful
Pregnancy:No information in human pregnancy
Women-Specific Information:Selzentry is safe to use while using birth control pills
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:www.selzentry.com
Patient Assistance:Viiv patient assistance program or 1-877-784-4842
Co-payment assistance


Combination Pills

Atripla

Brand Name: Atripla
Other Name(s):Sustiva plus Emtriva plus Viread
Generic Name(s):Efavirenz plus Emtricitabine plus Tenofovir
Class of Drug:2 NRTIs and 1 NNRTI
Common Side Effects:Same as those for the individual drugs that make up Atripla: dizziness, trouble sleeping, unusual dreams, drowsiness, nausea, headache, vomiting, trouble concentrating, rash
Serious Side Effects:Lactic acidosis, liver problems, lipodystrophy, kidney problems, bone problems, severe depression, strange thoughts, angry behavior, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Atripla is a one-pill, once-daily drug regimen (it does not have to be used with other HIV drugs). Get tested for hepatitis B (HBV) before taking Atripla. Because Emtriva and Viread also fight HBV, if you are co-infected with HBV and HIV, stopping Atripla may cause your HBV to get worse.
Pregnancy:There is evidence of an increased risk of birth defects in babies born to women who use Sustiva during pregnancy. Because Sustiva is one of the drugs that makes up Atripla, women should not take Atripla during pregnancy.
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the Emtriva and Viread in Atripla
Who Produces the Drug:Bristol-Myers Squibb and Gilead
Web Site for Drug Info:www.atripla.com
Patient Assistance:Atripla Patient Assistance Program or
1-866-290-4767
Co-payment assistance at 866-784-3431


Combivir

Brand Name: Combivir (Duovir in some countries outside the US)
Other Name(s):Retrovir plus Epivir
Generic Name(s):Zidovudine (AZT) plus Lamivudine (3TC)
Class of Drug:2 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Combivir: nausea, vomiting, loss of appetite, headaches, fatigue, trouble sleeping, diarrhea, cough, nasal symptoms (like a stuffy nose)
Serious Side Effects:Anemia, neutropenia, Lactic acidosis, liver problems, lipodystrophy, myopathy (muscle pain and weakness), peripheral neuropathy, pancreatitis
Special Considerations:Get tested for hepatitis B (HBV) before taking Combivir. Epivir fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Combivir may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects; short-term use of both the Retrovir and Epivir parts of Combivir demonstrated to be safe for mothers and infants
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs, especially the Retrovir part of Combivir
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Combivir
Patient Assistance:Bridges to Access or 1-866-728-4368
Co-payment assistance


Complera

Brand Name: Complera
Other Name(s):Emtriva plus Viread plus Edurant
Generic Name(s):Emtricitabine plus Tenofovir plus Rilpivarine
Class of Drug:2 NRTIs and 1 NNRTI
Common Side Effects:Same as those for the individual drugs that make up Complera: nausea, vomiting, diarrhea, loss of appetite, gas, headaches, rash, skin discoloration, trouble sleeping, depression, anxiety, dizziness, muscle aches, weakness
Serious Side Effects:Lactic acidosis, liver problems, lipodystrophy, kidney problems, bone problems, severe depression and suicidal thoughts
Special Considerations:Complera is a one-pill, once-daily drug regimen (it does not have to be used with other HIV drugs). It is only approved for people starting HIV treatment for the first time. Get tested for hepatitis B (HBV) before taking Complera. Emtriva and Viread fight HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Complera may cause your HBV to get worse.
Pregnancy:No information in human pregnancy
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the Emtriva and Viread in Complera
Who Produces the Drug:Gilead and Janssen
Web Site for Drug Info:Complera
Patient Assistance:Complera.com or 800-226-2056
Co-Pay Assistance at 877-505-6986


Epzicom

Brand Name: Epzicom (Kivexa in some countries outside the US)
Other Name(s):Epivir plus Ziagen
Generic Name(s):Lamivudine plus Abacavir
Class of Drug:2 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Epzicom: nausea, vomiting, diarrhea, headaches, dizziness, fatigue, trouble sleeping, depression
Serious Side Effects:Hypersensitivity reaction (watch for fever, rash, severe nausea, vomiting, or abdominal pain; and cough, sore throat, or difficulty breathing), Lactic acidosis, liver problems, lipodystrophy, peripheral neuropathy, pancreatitis
Special Considerations:Get tested for hepatitis B (HBV) before taking Epzicom. Epivir fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Epzicom may cause your HBV to get worse. HLA-B*5701 screening (for hypersensitivity reaction) is recommended before starting a Ziagen-containing regimen. Studies do not agree on whether taking the Ziagen part of Epzicom can increase your risk of heart disease. If you think you might be at increased risk of heart disease, you should talk to your health care provider about whether you should take Epzicom.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the NRTIs Epivir and Ziagen that make up Epzicom
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Epzicom/Kivexa
Patient Assistance:Bridges to Access or 1-866-728-4368
Co-payment assistance

Trizivir

Brand Name: Trizivir
Other Name(s):Retrovir plus Epivir plus Ziagen
Generic Name(s):Zidovudine plus Lamivudine plus Abacavir
Class of Drug:3 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Trizivir: nausea, vomiting, diarrhea, headaches, fatigue, trouble sleeping
Serious Side Effects:Hypersensitivity reaction (watch for fever, rash, severe nausea, vomiting, or abdominal pain; and cough, sore throat, or difficulty breathing), liver problems, lipodystrophy, peripheral neuropathy, pancreatitis, myopathy (muscle pain and weakness), Anemia, neutropenia
Special Considerations:Get tested for hepatitis B (HBV) before taking Trizivir. Because Epivir also fights HBV, if you are co-infected with HBV and HIV, stopping Trizivir may cause your HBV to get worse. HLA-B*5701 screening (for hypersensitivity reaction) is recommended before starting a Ziagen-containing regimen. Studies do not agree on whether taking the Ziagen part of Trizivir can increase your risk of heart disease. If you think you might be at increased risk of heart disease, you should talk to your health care provider about whether you should take Trizivir.
Pregnancy:No evidence of increased likelihood of birth defects; Retrovir, a part of Trizivir, is effective at reducing mother-to-child transmission.
Women-Specific InformtionWomen are more likely than men to develop lactic acidosis with long-term use of the 3 NRTIs in Trizivir, especially Retrovir
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Trizivir
Patient Assistance:Bridges to Access or 1-866-728-4368
Co-payment assistance

Truvada

Brand Name: Truvada
Other Name(s):Emtriva plus Viread
Generic Name(s):Emtricitabine plus Tenofovir
Class of Drug:2 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Truvada: nausea, vomiting, loss of appetite, diarrhea, gas, rash, headache, weakness, skin discoloration
Serious Side Effects:Kidney problems, bone problems, Lactic acidosis, liver problems, lipodystrophy
Special Considerations:Get tested for hepatitis B (HBV) before taking Truvada. Because both drugs fight HBV as well as HIV, if you are co-infected with HBV and HIV, stopping Truvada may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the 2 NRTIs in Truvada
Who Produces the Drug:Gilead
Web Site for Drug Info:www.truvada.com
Patient Assistance:Truvada Patient Assistance Program
1-800-226-2056
Co-payment assistance at 1-888-358-0398




This article was provided by The Well Project. You can find this article online by typing this address into your Web browser:
http://www.thebody.com/content/art58932.html

General Disclaimer: TheBody.com is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through TheBody.com should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.