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HIV Drug Chart/Overview

May 2012

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Combination Pills

Atripla

Brand Name: Atripla
Other Name(s):Sustiva plus Emtriva plus Viread
Generic Name(s):Efavirenz plus Emtricitabine plus Tenofovir
Class of Drug:2 NRTIs and 1 NNRTI
Common Side Effects:Same as those for the individual drugs that make up Atripla: dizziness, trouble sleeping, unusual dreams, drowsiness, nausea, headache, vomiting, trouble concentrating, rash
Serious Side Effects:Lactic acidosis, liver problems, lipodystrophy, kidney problems, bone problems, severe depression, strange thoughts, angry behavior, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Atripla is a one-pill, once-daily drug regimen (it does not have to be used with other HIV drugs). Get tested for hepatitis B (HBV) before taking Atripla. Because Emtriva and Viread also fight HBV, if you are co-infected with HBV and HIV, stopping Atripla may cause your HBV to get worse.
Pregnancy:There is evidence of an increased risk of birth defects in babies born to women who use Sustiva during pregnancy. Because Sustiva is one of the drugs that makes up Atripla, women should not take Atripla during pregnancy.
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the Emtriva and Viread in Atripla
Who Produces the Drug:Bristol-Myers Squibb and Gilead
Web Site for Drug Info:www.atripla.com
Patient Assistance:Atripla Patient Assistance Program or
1-866-290-4767
Co-payment assistance at 866-784-3431


Combivir

Brand Name: Combivir (Duovir in some countries outside the US)
Other Name(s):Retrovir plus Epivir
Generic Name(s):Zidovudine (AZT) plus Lamivudine (3TC)
Class of Drug:2 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Combivir: nausea, vomiting, loss of appetite, headaches, fatigue, trouble sleeping, diarrhea, cough, nasal symptoms (like a stuffy nose)
Serious Side Effects:Anemia, neutropenia, Lactic acidosis, liver problems, lipodystrophy, myopathy (muscle pain and weakness), peripheral neuropathy, pancreatitis
Special Considerations:Get tested for hepatitis B (HBV) before taking Combivir. Epivir fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Combivir may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects; short-term use of both the Retrovir and Epivir parts of Combivir demonstrated to be safe for mothers and infants
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of NRTIs, especially the Retrovir part of Combivir
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Combivir
Patient Assistance:Bridges to Access or 1-866-728-4368
Co-payment assistance


Complera

Brand Name: Complera
Other Name(s):Emtriva plus Viread plus Edurant
Generic Name(s):Emtricitabine plus Tenofovir plus Rilpivarine
Class of Drug:2 NRTIs and 1 NNRTI
Common Side Effects:Same as those for the individual drugs that make up Complera: nausea, vomiting, diarrhea, loss of appetite, gas, headaches, rash, skin discoloration, trouble sleeping, depression, anxiety, dizziness, muscle aches, weakness
Serious Side Effects:Lactic acidosis, liver problems, lipodystrophy, kidney problems, bone problems, severe depression and suicidal thoughts
Special Considerations:Complera is a one-pill, once-daily drug regimen (it does not have to be used with other HIV drugs). It is only approved for people starting HIV treatment for the first time. Get tested for hepatitis B (HBV) before taking Complera. Emtriva and Viread fight HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Complera may cause your HBV to get worse.
Pregnancy:No information in human pregnancy
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the Emtriva and Viread in Complera
Who Produces the Drug:Gilead and Janssen
Web Site for Drug Info:Complera
Patient Assistance:Complera.com or 800-226-2056
Co-Pay Assistance at 877-505-6986


Epzicom

Brand Name: Epzicom (Kivexa in some countries outside the US)
Other Name(s):Epivir plus Ziagen
Generic Name(s):Lamivudine plus Abacavir
Class of Drug:2 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Epzicom: nausea, vomiting, diarrhea, headaches, dizziness, fatigue, trouble sleeping, depression
Serious Side Effects:Hypersensitivity reaction (watch for fever, rash, severe nausea, vomiting, or abdominal pain; and cough, sore throat, or difficulty breathing), Lactic acidosis, liver problems, lipodystrophy, peripheral neuropathy, pancreatitis
Special Considerations:Get tested for hepatitis B (HBV) before taking Epzicom. Epivir fights HBV as well as HIV. If you are co-infected with HBV and HIV, stopping Epzicom may cause your HBV to get worse. HLA-B*5701 screening (for hypersensitivity reaction) is recommended before starting a Ziagen-containing regimen. Studies do not agree on whether taking the Ziagen part of Epzicom can increase your risk of heart disease. If you think you might be at increased risk of heart disease, you should talk to your health care provider about whether you should take Epzicom.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the NRTIs Epivir and Ziagen that make up Epzicom
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Epzicom/Kivexa
Patient Assistance:Bridges to Access or 1-866-728-4368
Co-payment assistance

Trizivir

Brand Name: Trizivir
Other Name(s):Retrovir plus Epivir plus Ziagen
Generic Name(s):Zidovudine plus Lamivudine plus Abacavir
Class of Drug:3 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Trizivir: nausea, vomiting, diarrhea, headaches, fatigue, trouble sleeping
Serious Side Effects:Hypersensitivity reaction (watch for fever, rash, severe nausea, vomiting, or abdominal pain; and cough, sore throat, or difficulty breathing), liver problems, lipodystrophy, peripheral neuropathy, pancreatitis, myopathy (muscle pain and weakness), Anemia, neutropenia
Special Considerations:Get tested for hepatitis B (HBV) before taking Trizivir. Because Epivir also fights HBV, if you are co-infected with HBV and HIV, stopping Trizivir may cause your HBV to get worse. HLA-B*5701 screening (for hypersensitivity reaction) is recommended before starting a Ziagen-containing regimen. Studies do not agree on whether taking the Ziagen part of Trizivir can increase your risk of heart disease. If you think you might be at increased risk of heart disease, you should talk to your health care provider about whether you should take Trizivir.
Pregnancy:No evidence of increased likelihood of birth defects; Retrovir, a part of Trizivir, is effective at reducing mother-to-child transmission.
Women-Specific InformtionWomen are more likely than men to develop lactic acidosis with long-term use of the 3 NRTIs in Trizivir, especially Retrovir
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Trizivir
Patient Assistance:Bridges to Access or 1-866-728-4368
Co-payment assistance

Truvada

Brand Name: Truvada
Other Name(s):Emtriva plus Viread
Generic Name(s):Emtricitabine plus Tenofovir
Class of Drug:2 NRTIs
Common Side Effects:Same as those for the individual drugs that make up Truvada: nausea, vomiting, loss of appetite, diarrhea, gas, rash, headache, weakness, skin discoloration
Serious Side Effects:Kidney problems, bone problems, Lactic acidosis, liver problems, lipodystrophy
Special Considerations:Get tested for hepatitis B (HBV) before taking Truvada. Because both drugs fight HBV as well as HIV, if you are co-infected with HBV and HIV, stopping Truvada may cause your HBV to get worse.
Pregnancy:No evidence of increased likelihood of birth defects
Women-Specific Information:Women are more likely than men to develop lactic acidosis with long-term use of the 2 NRTIs in Truvada
Who Produces the Drug:Gilead
Web Site for Drug Info:www.truvada.com
Patient Assistance:Truvada Patient Assistance Program
1-800-226-2056
Co-payment assistance at 1-888-358-0398
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This article was provided by The Well Project. Visit The Well Project's Web site to learn more about their resources and initiatives for women living with HIV. The Well Project shares its content with TheBody.com to ensure all people have access to the highest quality treatment information available. The Well Project receives no advertising revenue from TheBody.com or the advertisers on this site. No advertiser on this site has any editorial input into The Well Project's content.
 
See Also
HIV Medications: When to Start and What to Take -- A Guide From TheBody.com
More on HIV Medications

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