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HIV Drug Chart/Overview

May 2012

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Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

Edurant

Brand Name: Edurant
Other Name(s):RPV
Generic Name(s):Rilpivirine
Class of Drug:NNRTI
Common Side Effects:Rash, headache, trouble sleeping, depression, anxiety, dizziness, muscle aches
Serious Side Effects:Liver problems, lipodystrophy, severe depression and suicidal thoughts
Special Considerations:Only approved for people starting HIV treatment for the first time
Pregnancy:No information in human pregnancy
Who Produces the Drug:Tibotec
Web Site for Drug Info:www.edurant-info.com/
Patient Assistance:Johnson and Johnson Patient Assistance Foundation: www.jjpaf.org or 800-652-6227
Tibotec Patient Savings Program (for help with co-pays): 866-961-7169


Intelence

Brand Name: Intelence
Other Name(s):ETR
Generic Name(s):Etravirine
Class of Drug:NNRTI
Common Side Effects:Nausea, rash, diarrhea, peripheral neuropathy, headache, high blood pressure
Serious Side Effects:Hypersensitivity (rash, flu-like symptoms, and sometimes organ problems, including liver failure), Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Contact your health care provider immediately if symptoms of severe skin reactions develop
Pregnancy:No information in human pregnancy
Women-Specific Information:Women are more likely to experience nausea than men when taking Intelence
Who Produces the Drug:Tibotec
Web Site for Drug Info:www.intelence-info.com
Patient Assistance:Intelence Patient Assistance Program
800-652-6227
Tibotec Patient Savings Program (for help with co-pays): 866-961-7169


Rescriptor

Brand Name: Rescriptor
Other Name(s):DLV
Generic Name(s):Delavirdine
Class of Drug:NNRTI
Common Side Effects:Nausea, diarrhea, headaches, fatigue, rash, fever
Serious Side Effects:Stevens Johnson Syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling), liver problems (may include yellowing of the skin and eyes)
Special Considerations:People with low amounts of acid in their stomach (achlorhydria) should take Rescriptor with a liquid that contains some acid, like orange or cranberry juice
Pregnancy:No information in human pregnancy
Who Produces the Drug:Viiv Healthcare
Web Site for Drug Info:Rescriptor
Patient Assistance:Bridges to Access
866-728-4368
Viiv Healthcare Patient Assistance Program
877-784-4842
Co-payment assistance at www.mysupportcard.com/


Sustiva

Brand Name: Sustiva (or Stocrin outside the US)
Other Name(s):EFV
Generic Name(s):Efavirenz
Class of Drug:NNRTI
Common Side Effects:Nausea, diarrhea, headaches, fatigue, rash, trouble sleeping, confusion, drowsiness, abnormal dreams
Serious Side Effects:Severe mood changes (including anxiety, depression, suicidal thoughts, aggression), Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling), liver problems, lipodystrophy
Special Considerations:Women who are pregnant or may get pregnant should not use Sustiva-containing regimens
Pregnancy:There is evidence of an increased risk of birth defects in babies born to women who use Sustiva during pregnancy
Women-Specific Information:Because Sustiva reduces the levels of some hormonal contraceptives, talk to your health care provider about adding a reliable barrier method of contraception if you take Sustiva
Who Produces the Drug:Bristol-Myers Squibb
Web Site for Drug Info:www.sustiva.com
Patient Assistance:Sustiva Patient Assistance or 1-888-281-8981
Co-payment assistance at www.bmshivcopayprogram.com/


Viramune

Brand Name: Viramune
Other Name(s):NVP
Generic Name(s):Nevirapine
Class of Drug:NNRTI
Common Side Effects:Rash, nausea, headaches, fever, fatigue
Serious Side Effects:Liver damage, lipodystrophy, Stevens-Johnson syndrome (severe skin rash accompanied by fever, fatigue, muscle or joint aches, blisters, facial and tongue swelling)
Special Considerations:Women with CD4 cell counts greater than 250 (including pregnant women) and men with CD4 cell counts above 400 at the time of starting treatment have a higher risk of serious liver damage. Careful dosing and liver monitoring is needed when starting Viramune.
Pregnancy:No evidence of increased likelihood of birth defects. Evidence suggests that taking a drug regimen including Viramune while pregnant reduces mother-to-child transmission of HIV. Viramune is present in breast milk.
Women-Specific Information:Because Viramune reduces the levels of some hormonal contraceptives, talk to your health care provider about changing to or adding other methods of contraception if you take Viramune. Women taking Viramune are more likely than men to develop rash, and may also be more likely to develop liver damage.
Who Produces the Drug:Boehringer-Ingelheim
Web Site for Drug Info:www.viramune.com
Patient Assistance:Viramune Patient Assistance or 1-800-556-8317
Co-payment assistance -- speak to your health care provider about obtaining a Viramune Co-Pay Savings Card


Integrase Inhibitors

Isentress

Brand Name: Isentress
Other Name(s):RGV
Generic Name(s):Raltegravir
Class of Drug:Integrase inhibitors
Common Side Effects:diarrhea, nausea, headaches, trouble sleeping
Serious Side Effects:Liver toxicity, elevated levels of a muscle enzyme called creatine kinase
Special Considerations:Should be used with caution by people who are at increased risk for muscle problems like myopathy and rhabdomyolysis. Contact your health care provider if you experience unexplained muscle pain, tenderness, or weakness.
Pregnancy:No information in human pregnancy
Women-Specific Information:A recent study conducted by Merck showed Isentress to be safe and effective in women and blacks
Who Produces the Drug:Merck
Web Site for Drug Info:www.isentress.com
Patient Assistance:Merck Patient Assistance Program
1-800-850-3430
Co-payment assistance
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This article was provided by The Well Project. Visit The Well Project's Web site to learn more about their resources and initiatives for women living with HIV. The Well Project shares its content with TheBody.com to ensure all people have access to the highest quality treatment information available. The Well Project receives no advertising revenue from TheBody.com or the advertisers on this site. No advertiser on this site has any editorial input into The Well Project's content.
 
See Also
HIV Medications: When to Start and What to Take -- A Guide From TheBody.com
More on HIV Medications

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