In its natural or wild type state, HIV is not resistant to any particular drug and known drug levels are needed to suppress HIV replication. Drug-resistant HIV requires higher levels of the same drug to remain suppressed. However, because few if any direct comparisons have been made between the two types of tests, at this time no single test was determined better than any other. Both genotyping and phenotyping are useful and may be used differently in various settings (treatment management vs. drug development, etc.).
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