In Clinical Trial, Vaginal Gel PRO 2000 Found "Safe but Ineffective" at Preventing HIV Infection
September 20, 2010
A vaginal gel designed to protect women against HIV "was found to be safe but ineffective" in a clinical trial, Agence France-Presse reports, citing a study published online in the journal Lancet. The gel, PRO 2000, was tested in two different concentrations on 9,000 women in South Africa, Tanzania, Uganda and Zambia. The gel contains a "large charged polymer, which is intended to disrupt HIV's interaction with targeted cells." AFP notes PRO 2000 is "different" from the CAPRISA 004 vaginal gel, which was shown to be effective in clinical trials earlier this year and incorporates AIDS drug tenofovir into the gel (9/19). MedPage Today reports that "adherence was high" but "the incidence of HIV was much the same in both analyses" of the two different gel concentrations and the placebo (Smith, 9/19).
Experts Gathered for UNAIDS, WHO Meeting Recommend Follow-Up Studies of ARV-Containing Microbicide Gel Start Soon
This article was provided by Henry J. Kaiser Family Foundation. It is a part of the publication Kaiser Daily Global Health Policy Report. Visit the Kaiser Family Foundation's website to find out more about their activities, publications and services.
Add Your Comment:
(Please note: Your name and comment will be public, and may even show up in
Internet search results. Be careful when providing personal information! Before
adding your comment, please read TheBody.com's Comment Policy.)