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Women, Anemia and HIV/AIDS

May 2013

Table of Contents


What Is Anemia?

Anemia is a medical condition that occurs when you have a lower than normal amount of red blood cells (RBCs) in your body. It can also happen if your hemoglobin (HGB) level is below normal. HGB is a protein that uses iron to carry oxygen. It is found in RBCs and gives blood its red color. HGB carries oxygen from the lungs to the rest of the body. Oxygen is necessary for the body to make energy and carry out all its functions. If you have anemia, your body does not carry enough oxygen in your blood.

Anemia can be mild, moderate, or severe. It can also be temporary or a longer-lasting problem. With severe or long-lasting anemia, the lack of oxygen in the blood can damage the heart, brain, and other organs of the body. Very severe anemia can even cause death. The good news is, anemia can be identified and treated.

At first, anemia can be so mild that it goes unnoticed. Symptoms usually appear and get worse as the anemia gets worse. Symptoms can include:


What Causes Anemia?

There are many possible causes of anemia, including:


Anemia and HIV

Anemia has been a long-standing problem for people living with HIV (HIV+). Although serious anemia has become less common since people started using a combination of HIV drugs, anemia continues to affect up to three out of ten HIV+ people, and eight out of ten people living with AIDS. Factors that are linked to a greater likelihood of anemia in HIV+ people include:

Anemia is a common condition for HIV+ women, and it is often overlooked. If left untreated, anemia is strongly associated with HIV disease progression and an increased risk of death.


Women and Anemia

The most common type of anemia in the US is iron deficiency anemia, which is caused by a shortage of iron. According to the US Centers for Disease Control and Prevention (CDC), close to six million women between 15 and 49 years old are iron deficient, and almost half of these women will develop iron deficiency anemia. Worldwide, iron deficiency is the most common nutritional deficiency and has negative effects on both women and children.

Women are especially likely to develop iron deficiency anemia for several reasons. First, women aged 12 to 49 lose blood approximately once a month during their periods. Iron is needed to make the new blood that replaces the blood lost with each menstrual period. The risk of anemia is higher among women with periods that are especially long or include very heavy bleeding. Some women also lose iron from uterine fibroids that bleed slowly, or from bleeding caused by using intrauterine devices (IUDs) for birth control.

Second, women need extra iron during pregnancy for the proper development of their babies. In fact, pregnant women need 50 percent more iron than usual (27 mg per day instead of the usual 18 mg per day). Women also lose blood during childbirth. It is important for women who are pregnant or plan to become pregnant to have their iron levels checked and bring any symptoms of anemia to their health care providers' attention.


Diagnosis and Treatment

With diagnosis and treatment, the affects of anemia can be greatly reduced. Anemia is usually diagnosed by measuring HGB and hematocrit (HCT). HCT is the percentage of RBCs in the blood. HGB and HCT are measured as part of a routine blood test called a complete blood count (CBC). A CBC should be done as part of your regular health exams.

The treatment for anemia depends on the cause:

There are also medications that help your body make more red blood cells. These medications include the injectable drug erythropoietin or EPO (brand names Epogen and Procrit). Some people with severe anemia may need a blood transfusion. However, transfusions are a last resort.

Good communication with your health care provider will help determine the best treatment for you based on what is causing the anemia.


Taking Care of Yourself

Anemia is a common condition in HIV+ people, especially women. It can cause feelings of fatigue, lower your quality of life, and increase the chances that your HIV disease will get worse.

If you are feeling tired for unexplained reasons or experiencing any of the other symptoms listed above, talk to your health care provider. He or she can run tests to determine if anemia is the problem. If so, your health care provider will look for the cause and suggest treatment options. Treating anemia improves the health and survival of HIV+ people.




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