Can More People Be Put on ART Without Increased Cost?
With no end to the global funding retreat in sight, new strategies are required to change the way we provide treatment to the world's 33 million people infected with HIV.
On June 7-10, the Clinton Health Access Initiative (CHAI) hosted a conference, Opportunities to reduce the cost of anti-retroviral (ARV) treatment, to explore opportunities to significantly lower the costs of antiretroviral therapy (ART). Dose finding during drug development often maximizes tolerability but sometimes fails to explore minimally effective dosing. The earliest example of dose adjustment was AZT (zidovudine), which was initially tested at much higher doses (1500 mg daily compared with today's dose of 600 mg daily).View Full Article
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