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Can More People Be Put on ART Without Increased Cost?

Summer 2010

With no end to the global funding retreat in sight, new strategies are required to change the way we provide treatment to the world's 33 million people infected with HIV.

On June 7-10, the Clinton Health Access Initiative (CHAI) hosted a conference, Opportunities to reduce the cost of anti-retroviral (ARV) treatment, to explore opportunities to significantly lower the costs of antiretroviral therapy (ART). Dose finding during drug development often maximizes tolerability but sometimes fails to explore minimally effective dosing. The earliest example of dose adjustment was AZT (zidovudine), which was initially tested at much higher doses (1500 mg daily compared with today's dose of 600 mg daily).

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Reader Comments:

Comment by: Barbara B. (Mountain View CA) Fri., Aug. 20, 2010 at 2:58 pm EDT
Many of my associates in the international medical community have spent sleepless nights over the curtailed funding of HIV programs in Africa. You give us hope that the people suffering from HIV will not be abandoned.
B.E. Bonar Health Partnership
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Comment by: Michael Luciano (North Charleston, SC) Fri., Aug. 20, 2010 at 12:13 am EDT
Given the fact that the nationwide ADAP waiting-list total is about to reach 3000 and threats to Medicare and Medicaid funding loom ever more real, I think we need to recognize that the US is, for too many of us, a "resource-poor" environment. Shouldn't we be pushing for similar studies here??
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