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Oral Candidiasis (Thrush)

From Project Inform

November 2005

Treating Oral Candidiasis

Drug Name Dose Side Effects Notes
Topical Therapies
Clotrimazole
(Mycelex) trouches 		10mg 4-5 times daily for 1-2 weeks May cause altered taste and stomach upset Suck slowly; do not chew or swallow whole
Nystatin
(Mycostatin) Pastille 		1-2 pastilles
4-5 times daily 		May cause irritation in the mouth; nausea Suck slowly; do not chew or swallow whole
Nystatin
(Mycostatin) oral suspension 		5ml four times daily for 7-14 days May cause stomach upset Swish around mouth before swallowing
Systemic Therapies
Ketoconazole
(Nizoral) tablet 		200mg a day, 7-14 days;
400mg day, 14-21 days* 		Nausea, vomiting, stomach pain; liver toxicity Monitor liver function while taking this drug; take with food
Itraconazole
(Sporanox) 		100mg a day, 7-14 days;
200mg a day, 14-21 days* 		Nausea, vomiting, stomach pain; liver toxicity Monitor liver function while taking this drug
Fluconazole
(Diflucan) 		200mg a day, 7-14 days;
200mg a day, 14-21 days* 		Nausea, vomiting, stomach pain; liver toxicity Monitor liver function while taking this drug
Amphotericin B (Fungizone)
Amphotericin B lipid complex (Abelcet) 		100mg a day four times daily (oral suspension);
0.5mg/kg a day, 14-21 days (intravenous)* 		For intravenous form: kidney toxicity, electrolyte losses, fever, chills, sweats For oral suspension, swish around mouth before swallowing; monitor kidney function
Others
Gentian violet
(1% solution in water) 		Applied to affected areas twice a day for three days May cause swelling Available over-the-counter; may be useful for recurrent infections when applied every 7 days for 1 month; messy application

* Esophageal Candidiasis



  
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This article was provided by Project Inform. Visit Project Inform's website to find out more about their activities, publications and services.
 
 

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