Hepatitis B: Sex Hormone Explains Higher Liver Cancer Risk in Men
June 8, 2010
Men with hepatitis B are more likely than women to develop liver cancer, and serum concentrations of male sex hormones may play a part, a new study suggests.
Working with mice with the hepatitis B virus, the team genetically modified some to lack androgen receptors in the liver. By 22 weeks, more than 90 percent of mice with androgen receptors had developed tumors, compared with 27 percent of mice without receptors. Changing the hepatic androgen receptors did not affect overall androgen levels or have any apparent toxic effect.View Full Article
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