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Medical News

Effectiveness of an HIV/STD Risk-Reduction Intervention for Adolescents When Implemented by Community-Based Organizations: A Cluster-Randomized Controlled Trial

May 13, 2010

The current study evaluates the effectiveness of an HIV/STD risk-reduction intervention when implemented by community-based organizations (CBOs).


The cluster-randomized controlled trial involved 86 CBOs serving African Americans ages 13 to 18. The CBOs were randomized to implement either an HIV/STD risk-reduction intervention whose efficacy has been demonstrated, or a health-promotion intervention (control). The CBOs agreed to implement six intervention groups; a random half of the groups completed three-, six- and 12-month follow-up assessments. Consistent condom use in the three months prior to each follow-up assessment, averaged over the follow-up assessments, was the primary outcome. The study involved a total of 1,707 adolescents: 863 in HIV/STD-intervention CBOs, and 844 in control-intervention CBOs.

The result indicate the youths in the HIV/STD-intervention CBOs were more likely to report consistent condom use (odds ratio [OR]=1.39; 95 percent confidence interval [CI]=1.06, 1.84) than the youths in the control condition. Also, compared to the control group, teens in the HIV/STD intervention group reported a greater proportion of condom-protected intercourse (ß=0.06; 95 percent CI=0.00, 0.12).

"This is the first large, randomized intervention trial to demonstrate that CBOs can successfully implement an HIV/STD risk-reduction intervention whose efficacy has been established," the authors concluded.

Back to other news for May 2010

Adapted from:
American Journal of Public Health
04.01.2010; Vol. 100; No. 4: P. 720-726; John B. Jemmott, III, Ph.D.; Loretta S. Jemmott, Ph.D.; Geoffrey T. Fong, Ph.D.; Knashawn H. Morales, Sc.D.

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This article was provided by CDC National Prevention Information Network. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update.
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