HIV, Community-Associated Methicillin-Resistant Staphylococcus aureus Epidemics Intersect
April 5, 2010
People with HIV have a heightened risk of community-associated methicillin-resistant Staphylococcus aureus infection (CA-MRSA), according to a report published recently.
Incidence among HIV patients increased from 411 cases per 100,000 in period 1 to 1,474 cases per 100,000 (relative risk 3.6, P less than 0.001) in period 2. In addition, cases in period 1 clustered in an area, 6.3 kilometers in diameter, overlapping high-risk ZIP codes (where there was a high density of individuals with prior incarceration). By period 2, CA-MRSA cases were spread throughout Cook County. Incidence increased significantly among hospitalized HIV patients, from 190 cases per 100,000 patients in period 1 to 779 cases per 100,000 in period 2.
"Risks for CA-MRSA by multivariate analyses were residence in alternative housing (e.g., shelters), residence in high-risk ZIP codes, younger age, and infection in period 2," according to the authors.
"Our study shows an association between HIV and CA-MRSA," said Popovich, adding that his team wants to study factors behind the link. The risk may be amplified by "overlapping community-based social networks of high-risk patients," he said.
In an earlier study by some of the same researchers, CA-MRSA had grown overall in much of the same area, though methicillin-susceptible strains remained stable.
The full report, "Community-Associated Methicillin-Resistant Staphylococcus aureus and HIV: Intersecting Epidemics," was published in Clinical Infectious Diseases (2010;50:979-987).
03.26.2010; Michael Smith
This article was provided by U.S. Centers for Disease Control and Prevention. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update. Visit the CDC's website to find out more about their activities, publications and services.