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New Heat-Stable Form of Norvir Approved

February 2010

On February 10, 2010, the FDA approved a new heat-stable form of Norvir (ritonavir) 100mg tablets, which do not need to be refrigerated. The daily dose is 600mg taken twice a day. When used with other protease inhibitors, its dose should be reduced. The tablets are white and oval in shape, with "A NK" on the pill. The soft gel capsule and liquid forms of Norvir are still available.

This new tablet must be taken with meals, unlike the soft gel capsule. It should be swallowed whole to maximize its effectiveness and not chewed, broken or crushed. The prescription label warns that people who switch from the capsule to the tablet may experience more stomach and abdominal side effects, such as nausea, vomiting, pain or diarrhea. These side effects may decrease over time.

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