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Key Retrovirus Enzyme Grown in Lab

February 1, 2010

A study published on Sunday in the journal Nature has shed light on the enzyme integrase, "which is found in retroviruses like HIV and is a target for some of the newest HIV medicines," Reuters reports. Scientists at the Imperial College London and Harvard University grew a crystal of integrase in the lab allowing them to see the enzyme's structure. According to the news service, the scientists "said that having the integrase structure means researchers can begin fully to understand how integrase inhibitor drugs work, how they might be improved, and how to stop HIV developing resistance to them," according to the news service (Kelland, 2/1).

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