Liver Conference Becomes Defining Moment
November 10, 2009
The Liver Conference held in Boston October 30-Nov 3 was in many ways a defining moment for significant changes in Hepatitis C (HCV) in two important ways. First new classes of drugs to treat HCV are in early and mid stage clinical trials, including protease and polymerase inhibitors. Strategies to use these new classes of drugs together -- without pegylated alpha interferon and ribavirin, which are highly toxic and not highly effective in HCV genotype 1 -- are ushering in a new era of treating hepatitis C disease. Several other studies of the newer drug classes were presented that offer different pros and cons in terms of dosing and toxicities yet it will be some time before the new drugs are proven effective and ready for prime time. It is extremely encouraging to see these developments for both mono-infected Hepatitis C mono-infection and HCV and HIV co-infection.View Full Article
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