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HPV (Human Papillomavirus)

July 2009

What is HPV?

HPV (human papillomavirus) is a sexually transmitted virus. It is passed on through genital contact (such as vaginal and anal sex). It is also passed on by skin-to-skin contact. At least 50% of people who have had sex will have HPV at some time in their lives.

Why haven't I heard of HPV?

HPV is not a new virus. But many people don't know about it. Most people don't have any signs. HPV may go away on its own-- without causing any health problems.

Who can get HPV?

Anyone who has ever had genital contact with another person may have HPV. Both men and women may get it -- and pass it on -- without knowing it. Since there might not be any signs, a person may have HPV even if years have passed since he or she had sex.

What makes a person more likely to get HPV?

Most people who have sex may get HPV. You are more likely to get HPV if you have:

If there are no signs, why do I need to worry about HPV?

There are over 100 different kinds of HPV and not all of them cause health problems. Some kinds of HPV may cause problems like genital warts, cervical cancer or cancer of the vagina or vulva. HPV types 16 and 18 cause about 70% of cervical cancers. HPV types 6 and 11 cause about 90% of genital warts. HPV types 6 and 11 cause 20-50% of vulvar cancers and 60-65% of vaginal cancers.

Is there a cure for HPV?

There is no cure for the virus (HPV) itself. There are treatments for the health problems that HPV can cause, such as genital warts, cervical changes, and cervical cancer.

What should I know about genital warts?

There are many treatment choices for genital warts. But even after the warts are treated, the virus might still be there and may be passed on to others. If genital warts are not treated they may go away, stay the same, or increase in size or number, but they will not turn into cancer.

What should I know about cervical cancer?

All women should get regular Pap tests. The Pap test looks for cell changes caused by HPV. The test finds cell changes early -- so the cervix can be treated before the cells turn into cancer. This test also can also find cancer in its early stages so it can be treated before it becomes too serious. It is rare to die from cervical cancer if the disease is caught early.

What should I know about vaginal or vulvar cancer?

Vaginal cancer is cancer of the vagina (birth canal). Vulvar cancer is cancer of the clitoris, vaginal lips, and opening to the vagina. Both of these kinds of cancer are very rare. Not all vaginal or vulvar cancer is caused by HPV.

Is there a test for HPV?

Yes. It tests for the kinds of HPV that may lead to cervical cancer. The FDA approved the HPV test to be used for women over 30 years old. It may find HPV even before there are changes to the cervix. Women who have the HPV test still need to get the Pap test.

Can I lower my chances of getting HPV?

What is the HPV vaccine and how does it work?

The vaccine, called Gardasil, mimics the disease and creates resistance. It is NOT a live or a dead virus. It prevents infection with HPV types 6, 11, 16 and 18.

Is it safe?

Tests of the vaccine showed some minor problems. Some people had a headache, slight fever, nausea, or fainting. Others had redness, bruising, pain or swelling on their skin where they got the shot.

Some people have fainted and had jerking or seizure-like movements after getting the shot. Some people who have fainted have fallen and hurt themselves.

You should be seated or lying down when you get the shot. Make sure to stay at the doctor's office or clinic and continue to stay seated or lying down for at least 15 minutes so they can watch for any problems.

Is it effective?

Gardasil is between 95-100% effective against HPV types 6, 11, 16, 18.

Who should get the HPV vaccine?

The FDA has approved Gardasil for girls and women ages 9 to 26. It is best to get the shot before the start of sexual activity. It is NOT recommended for women over age 26.

How many shots do you need?

There are three shots. Once you get the first shot, you need a second shot two months later.  You need to get a third shot six months after you get the first shot.

How long are you protected?

Since the vaccine is new, more studies need to be done. For example, the FDA does not know if you will need to have a booster after a couple of years.

Should I get the vaccine if I already have HPV?

The vaccine will not treat or cure HPV. It may help people who have one type of HPV from being infected with the other types. For example, if you have type 6, it may protect you from getting type 16.

Can I catch HPV from getting the vaccine?

No. The vaccine does not contain the HPV virus.

To learn more:

FDA Center for Biologics Evaluation and Research




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