ACRIA Trials In Progress

• Pomegranate Juice
• Ibalizumab
• Crofelemer for Diarrhea
• Avandia and Serostim
• Isentress in Pregnant Women
• IMPACT: Reyataz Resistance

Pomegranate Juice

People who have not taken HIV meds for at least 90 days will drink pomegranate juice or placebo juice daily for 10 to 18 weeks to study its effect on the heart, quality of life, and HIV viral load.

Ibalizumab

People who have taken HIV drugs will receive infusions of ibalizumab (a monoclonal antibody designed to block HIV entry into CD 4 cells) once or twice a month for 48 weeks, along with other HIV drugs.

Crofelemer for Diarrhea

People 18 and older who have persistent diarrhea will take crofelemer (a new anti-diarrhea drug) or placebo tablets for 6 weeks. Then everyone will take crofelemer for 5 months.

Avandia and Serostim

People with insulin resistance will take Avandia (rosiglitazone), or Serostim (growth hormone), or both for 6 months to see how they affect blood sugar, insulin levels, and body shape.

Isentress in Pregnant Women

Pregnant women who are already taking Isentress will give several blood samples on two separate days in order to find the optimum dose of the drug during pregnancy. Compensation is provided.

IMPACT : Reyataz Resistance

People who have developed resistance to Reyataz will come in for one day of blood tests to study the I50L mutation.

For more information on these trials, contact us at 212-924-3934, ext. 121.

Want to read more articles in the Fall 2008 issue of Achieve? Click here.