Recreational Drug Use and T Lymphocyte Subpopulations in HIV-Uninfected and HIV-Infected Men
June 13, 2008
Noting that the effects of recreational drugs on CD4 and CD8 T cells in humans are not well understood, the authors conducted a longitudinal analysis of men who have sex with men (MSM) to define associations between self-reported use of marijuana, cocaine, poppers and amphetamines, and CD4 and CD8 T cell parameters in HIV-infected and -uninfected MSM.
"These results indicate that use of these substances does not adversely affect the numbers and percentages of circulating CD4 and CD8 T cells in either HIV-uninfected or -infected MSM," the researchers concluded.
Drug and Alcohol Dependence
04.01.2008; Vol. 94; No. 1-3: P. 165-171; Chun Chao, Lisa P. Jacobson, Donald Tashkin, Otoniel Martinez-Maza, Michael D. Roth, Joseph B. Margolick, Joan S. Chmiel, Charles Rinaldo, Zuo-Feng Zhang, Roger Detels