HIV Drug Linked to Serious Liver Side Effects, Health Canada Warns
May 16, 2008
Canadian health officials and Tibotec, a division of drug maker Janssen-Ortho, are advising patients taking Prezista (darunavir) that serious liver side effects have been linked to the drug. Prezista is used, in combination with ritonavir and other HIV drugs, for patients who have failed other antiretroviral therapy.
Patients with liver problems are at greater risk of Prezista side effects, the warning says.
Health Canada urges patients taking Prezista to contact their physician immediately if they experience any of the following symptoms: dark urine, yellowing of the skin, abdominal pain (especially on the right side bellow the ribs), general itchiness, decreased appetite, nausea, vomiting or fatigue. Patients should not stop taking Prezista without first consulting their doctor or pharmacist.
For more information, visit www.janssen-ortho.com/JOI/pdf_files/Prezista_PC_E.pdf.
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This article was provided by Henry J. Kaiser Family Foundation. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update. Visit the Kaiser Family Foundation's website to find out more about their activities, publications and services.