Reproductive Tract Infections Among Women Attending a Gynecology Outpatient Department in Vientiane, Lao People's Democratic Republic
November 1, 2007
By clinically and microbiologically identifying reproductive tract infections (RTI), including sexually transmitted infections (STI), the researchers monitored the antibiotic susceptibility of Neisseria gonorrhoeae among women attending a gynecology outpatient department in Vientiane, Laos.
In a clinical and laboratory-based cross-sectional study, women ages 15-49 underwent a pelvic examination in which specimens were taken for laboratory testing.
Of 1,125 study participants, 82 percent clinically presented with an RTI syndrome. However, only 64 percent had an etiologically diagnosed RTI, including 11 percent with an STI. Endogenous infections were most prevalent (candidiasis 40 percent; bacterial vaginosis 25 percent), followed by STI (Chlamydia trachomatis 4.1 percent; N. gonorrhea (NG) and Trichomonas vaginalis, both 3.7 percent). The 41 NG isolates showed 20 percent resistance to ciprofloxacin, 98 percent to penicillin, and complete to tetracycline.
The researchers concluded that the high RTI/STI levels, combined with high NG resistance, emphasize that concurrent with syndromic case management, periodic evaluations of etiological diagnosis should be available to ensure adequacy of treatment algorithms and prescribed medications.
Sexually Transmitted Diseases
10.2007; Vol. 34; No. 10: P. 791-795; Amphoy Sihavong, M.D., M.Med.Sc.; Traykhouane Phouthavane, D.M.M.; Cecilia Stalsby Lundborg, Ph.D.; Khanthanouvieng Sayabounthavong, M.D., M.S.; Lamphone Syhakhang, Ph.D.; Rolf Wahlstrom, M.D., Ph.D.