August 23, 2013
Brand Name: Norvir
Other Name(s): RTV
Drug Class: Protease Inhibitors
Approved Use: Treatment of HIV Infection
Ritonavir can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), severe allergic reactions, heart rhythm problems, and life-threatening drug interactions.
Contact your health care provider right away if you have any of the following symptoms that may signal liver problems:
Contact your health care provider right away if you have any of the following symptoms that may signal pancreatitis:
Contact your health care provider right away if you have any of the following symptoms that may signal heart rhythm problems:
Contact your health care provider right away if you develop a rash. Stop taking ritonavir and get medical help right away if you have any of the following symptoms that may signal a severe allergic reaction:
Taking ritonavir with certain other medicines (sedative hypnotics, antiarrhythmics, or ergot alkaloid preparations) may result in serious and/or life-threatening side effects.
While taking ritonavir, it is important to keep all of your appointments with your health care provider.
Ritonavir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children older than age 1 month. Ritonavir is always used in combination with other anti-HIV medicines.
Ritonavir is a type of anti-HIV medicine called a protease inhibitor (PI). Ritonavir works by blocking protease, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood.
Ritonavir does not cure HIV/AIDS. It is not known if ritonavir reduces the risk of passing HIV to other people.
Before taking ritonavir, tell your health care provider:
Ritonavir comes in the following forms and strengths:
Take ritonavir according to your health care provider's instructions.
Take ritonavir with meals. Swallow ritonavir tablets whole. Do not chew, break, or crush the tablets before swallowing. Ritonavir oral solution is a peppermint- or caramel-flavored liquid that can be taken alone or combined with 8 ounces of chocolate milk, Ensure, or Advera to improve the taste. (When mixed with these fluids, ritonavir oral solution should be taken within 1 hour of mixing.) Always shake the oral solution well before each use.
Always take ritonavir in combination with other anti-HIV medicines.
If you take too much ritonavir, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room right away.
For more information on how to take ritonavir, see the FDA drug labels for ritonavir tablets, capsules, and oral solution from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
Take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
Ritonavir can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), severe allergic reactions, heart rhythm problems, and life-threatening drug interactions. (See the WARNING above.)
Other possible side effects of ritonavir include:
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of ritonavir. Ask your health care provider or pharmacist for more information on possible side effects of ritonavir.
More information about ritonavir is available: