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Information
An Overview of Norvir (Ritonavir)

February 11, 2015

Norvir DS100NorvirRitonavir-Norvir 100 mg tablet

Brand Name: Norvir
Other Name(s): RTV
Drug Class: Protease Inhibitors
Approved Use: Treatment of HIV Infection

Chemical Image:

ritonavir

ritonavir
Molecular Weight: 720.955

WARNING:

Ritonavir can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), heart rhythm problems, severe allergic reactions, and life-threatening drug interactions.

Contact your health care provider right away if you have any of the following symptoms that may be a sign of liver problems:

Contact your health care provider right away if you have any of the following symptoms that may be a sign of pancreatitis:

Contact your health care provider right away if you have any of the following symptoms that may be a sign of heart rhythm problems:

Contact your health care provider right away if you develop a rash. Stop taking ritonavir and get medical help right away if you have any of the following symptoms that may be a sign of a severe allergic reaction:

Taking ritonavir with certain other medicines (including sedative hypnotics, antiarrhythmics, or ergot alkaloid preparations) may result in serious and/or life-threatening drug interactions. Before taking ritonavir, tell your health care provider about all medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Ritonavir oral solution contains a large amount of alcohol. Accidentally drinking more than the recommended dose of ritonavir could make a toddler or young child sick from too much alcohol. If this happens, call your local poison control center (1-800-222-1222) or hospital emergency room immediately.

While taking ritonavir, it is important to keep all of your appointments with your health care provider.


What Is Ritonavir?

Ritonavir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children older than age 1 month. Ritonavir is always used in combination with other HIV medicines.

Ritonavir belongs to a class (group) of HIV drugs called protease inhibitors (PIs). PIs block an HIV enzyme called protease. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking protease, PIs prevent HIV from multiplying and can reduce the amount of HIV in the body.

HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV treatment regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission.


What Should I Tell My Health Care Provider Before Taking Ritonavir?

Before taking ritonavir, tell your health care provider:


How Should I Take Ritonavir?

Ritonavir (brand name: Norvir) comes in the following forms and strengths:

Take ritonavir according to your health care provider's instructions.

Take ritonavir with meals.

Swallow ritonavir tablets whole. Do not chew, break, or crush the tablets before swallowing.

Ritonavir oral solution is a peppermint- or caramel-flavored liquid that can be taken alone or mixed with 8 ounces of chocolate milk, Ensure, or Advera to improve the taste. (When mixed with these fluids, ritonavir oral solution should be taken within 1 hour of mixing.) Always shake the oral solution well before each use.

Ritonavir oral solution contains a large amount of alcohol. Accidentally drinking more than the recommended dose of ritonavir could make a toddler or young child sick from too much alcohol. If this happens, call your local poison control center (1-800-222-1222) or hospital emergency room immediately.

Always take ritonavir in combination with other HIV medicines.

If you take too much ritonavir, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.

For more information on how to take ritonavir, see the FDA drug labels for ritonavir tablets, capsules, and oral solution, from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)


What Should I Do if I Forget a Dose?

If you miss a dose of ritonavir, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.


What Side Effects Can Ritonavir Cause?

Ritonavir can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), heart rhythm problems, severe allergic reactions, and life-threatening drug interactions. (See the WARNING above.)

Other possible side effects of ritonavir include:

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of ritonavir. To learn more about possible side effects of ritonavir, read the drug label or package insert or talk to your health care provider or pharmacist. The AIDSinfo fact sheet on HIV Medicines and Side Effects also includes information that may apply to ritonavir.

You can also report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online at www.accessdata.fda.gov/scripts/medwatch/.


How Should Ritonavir Be Stored?

Store ritonavir in the container that it came in and keep the container tightly closed. Follow specific storage instructions for ritonavir tablets, capsules, and oral solution.

Ritonavir oral solution:

Ritonavir tablets:

Ritonavir capsules:

Keep ritonavir and all medicines out of reach of children. Throw away ritonavir that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.


Where Can I Find More Information About Ritonavir?

More information about ritonavir is available:


Manufacturer Information

AbbVie Inc.
800-633-9110

The above Patient Version drug summary is based on the following FDA label(s): Capsule; Solution, tablet.




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