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An Overview of Kaletra (Lopinavir/Ritonavir)

August 23, 2013

low-PIN-a-veer, rit-ON-uh-veer

Kaletra 200-50 mgKaletra

Brand Name: Kaletra
Other Name(s): LPV/RTV, LPV/r
Drug Class: Protease Inhibitors
Approved Use: Treatment of HIV Infection

WARNING:

Kaletra can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), heart rhythm problems, severe allergic reactions, and life-threatening drug interactions.

Contact your health care provider right away if you have any of the following symptoms that may signal liver problems:

Contact your health care provider right away if you have any of the following symptoms that may signal pancreatitis:

Contact your health care provider right away if you have any of the following symptoms that may signal heart rhythm problems:

Contact your health care provider right away if you develop a skin rash. This could be a sign of a severe allergic reaction.

Babies taking Kaletra oral solution may have side effects. (Kaletra oral solution contains alcohol and propylene glycol.) Contact your health care provider right away if your baby appears too sleepy or his/her breathing has changed.

Taking Kaletra with certain other medicines may result in serious and/or life-threatening side effects.

While taking Kaletra, it is important to keep all of your appointments with your health care provider.


What is Kaletra?

Kaletra is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 14 days of age and older. Kaletra is a combination of the two drugs lopinavir and ritonavir. Kaletra is always used in combination with other anti-HIV medicines.

Kaletra contains the following two anti-HIV medicines: lopinavir and ritonavir. Lopinavir and ritonavir are types of anti-HIV medicines called protease inhibitors (PIs). PIs block protease, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood.

Kaletra does not cure HIV/AIDS. It is not known if Kaletra reduces the risk of passing HIV to other people.


What should I tell my health care provider before taking Kaletra?

Before taking Kaletra, tell your health care provider:


How should I take Kaletra?

Kaletra comes in the following forms and strengths:

Take Kaletra according to your health care provider's instructions.

Kaletra tablets can be taken with or without food and should be swallowed whole. Do not chew, break, or crush the tablets. Take Kaletra oral solution and capsules with food.

If you are also taking the anti-HIV medicine didanosine (brand name: Videx; Videx EC):

Always take Kaletra in combination with other anti-HIV medicines.

If you take too much Kaletra, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room.

For more information on how to take Kaletra, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)


What should I do if I forget a dose?

Take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.


What side effects can Kaletra cause?

Kaletra can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), heart rhythm problems, severe allergic reactions, and life-threatening drug interactions. (See the WARNING above.)

Other possible side effects of Kaletra include:

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Kaletra. Ask your health care provider or pharmacist for more information on possible side effects of Kaletra.


How should Kaletra be stored?


Where can I find more information about Kaletra?

More information about Kaletra is available:


Manufacturer Information

Abbott Laboratories
847-937-6100




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