An Overview of Combivir (AZT/3TC)
September 13, 2012
Brand Name: Combivir
Combivir can cause serious, life-threatening side effects. These include blood disorders (including severe anemia), lactic acidosis (a buildup of acid in the blood), liver problems, and muscle disorders.
Contact your health care provider right away if you have any of the following symptoms that may signal a blood disorder:
Contact your health care provider right away if you have any of the following symptoms that may signal lactic acidosis:
Contact your health care provider if you have any of the following symptoms that may signal liver problems:
Tell your health care provider if you have or have ever had any disease or swelling of the muscles. Contact your health care provider right away if have muscle pain or weakness.
Severe worsening of liver disease has occurred in some people co-infected with hepatitis B virus (HBV) and HIV when they stopped treatment with lamivudine, an anti-HIV medicine included in Combivir. Worsening of liver disease, sometimes causing death, has also occurred in people co-infected with hepatitis C virus (HCV) and HIV who were taking anti-HIV medicines and also being treated for HCV with interferon with or without ribavirin. Tell your health care provider about any side effects you have.
While taking Combivir, it is important to keep all of your appointments with your health care provider.
What is Combivir?
Combivir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. Combivir is always used in combination with other anti-HIV medicines.
Combivir contains the following two anti-HIV medicines combined in one pill: lamivudine and zidovudine. Lamivudine and zidovudine are types of anti-HIV medicines called nucleoside reverse transcriptase inhibitors (NRTIs). NRTIs block HIV reverse transcriptase, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood.
Combivir does not cure HIV/AIDS. It is not known if Combivir reduces the risk of passing HIV to other people.
What should I tell my health care provider before taking Combivir?
Before taking Combivir, tell your health care provider:
This article was provided by AIDSinfo. Visit the AIDSinfo website to find out more about their activities and publications.
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