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An Overview of Combivir (AZT/3TC)

August 23, 2013

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How should I take Combivir?

Combivir comes in tablet form. Each tablet contains:

  • 150 mg lamivudine (brand name: Epivir).
  • 300 mg zidovudine (brand name: Retrovir).

Take Combivir according to your health care provider's instructions.

Always take Combivir in combination with other anti-HIV medicines. Take Combivir with or without food.

If you take too much Combivir, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room right away.

For more information on how to take Combivir, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

What side effects can Combivir cause?

Combivir can cause serious, life-threatening side effects. These include blood disorders, lactic acidosis (a buildup of acid in the blood), liver problems, and muscle disorders. (See the WARNING above.)

Other possible side effects of Combivir include:

  • Changes in the immune system (immune reconstitution inflammatory syndrome).
  • Changes in body fat (lipodystrophy).

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Combivir. Ask your health care provider or pharmacist for more information on side effects of Combivir.

How should Combivir be stored?

  • Store Combivir between 36°F and 86°F (2°C to 30°C) and away from excessive heat and moisture.
  • Keep the medicine in its original container and keep the container tightly closed.
  • Throw away Combivir that is no longer needed or expired (out of date).
  • Keep Combivir and all medicines out of reach of children.

Where can I find more information about Combivir?

More information about Combivir is available:

Manufacturer Information


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This article was provided by AIDSinfo. Visit the AIDSinfo website to find out more about their activities and publications.
See Also
More on HIV Medications
More on Combivir (AZT/3TC)

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