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An Overview of Lexiva (Fosamprenavir, Telzir)

May 3, 2015

Lexiva (Fosamprenavir, Telzir)Lexiva bottle

Brand Name: Lexiva
Other Name: fosamprenavir calcium, FOS-APV, FPV
Drug Class: Protease Inhibitors
Approved Use: Treatment of HIV Infection

Chemical Image

fosamprenavir calcium

fosamprenavir calcium
Molecular Weight: 623.6736


Fosamprenavir can cause serious, life-threatening side effects. These include severe skin reactions or rash.

Stop taking fosamprenavir and contact your health care provider right away if you have a rash and have any of the following symptoms:

Taking fosamprenavir with certain other medicines may result in serious and/or life-threatening side effects. Tell your health care provider about other medicines you take.

While taking fosamprenavir, it is important to keep all of your appointments with your health care provider.

What Is Fosamprenavir?

Fosamprenavir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 4 weeks of age and older. Fosamprenavir is always used in combination with other HIV medicines.

Fosamprenavir belongs to a class (group) of HIV medicines called protease inhibitors (PIs). PIs block an HIV enzyme called protease. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking protease, PIs prevent HIV from multiplying and can reduce the amount of HIV in the body.

HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission.

What Should I Tell My Health Care Provider Before Taking Fosamprenavir?

Before taking fosamprenavir, tell your health care provider:

How Should I Take Fosamprenavir?

Fosamprenavir comes in two forms, under the brand name Lexiva:

Take fosamprenavir according to your health care provider's instructions.

Take fosamprenavir tablets with or without food. Adults should take the fosamprenavir oral suspension without food. Children should take the oral suspension with food. If your child vomits within 30 minutes after taking a dose of fosamprenavir, the dose should be repeated. Shake the oral suspension vigorously before each use.

Always take fosamprenavir in combination with other HIV medicines.

If you take too much fosamprenavir, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.

For more information on how to take fosamprenavir, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)

What Should I Do if I Forget a Dose?

If you miss a dose of fosamprenavir, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

What Side Effects Can Fosamprenavir Cause?

Fosamprenavir can cause serious, life-threatening side effects. These include severe skin reactions or rash. Taking fosamprenavir with certain other medicines may cause serious and/or life-threatening side effects. (See the WARNING above.)

Other possible side effects of fosamprenavir include:

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of fosamprenavir. To learn more about possible side effects of fosamprenavir, read the drug label or package insert or talk to your health care provider or pharmacist.

The AIDSinfo fact sheet on HIV Medicines and Side Effects also includes information that may apply to fosamprenavir.

You can also report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online at

How Should Fosamprenavir Be Stored?

Where Can I Find More Information About Fosamprenavir?

More information about fosamprenavir is available:

Manufacturer Information

ViiV Healthcare

The above Patient Version drug summary is based on the following FDA label(s): Suspension, tablet (film coated).

This article was provided by AIDSinfo. You can find this article online by typing this address into your Web browser:

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