Transcript of The Body's Live Chat on Fuzeon (T-20, Enfuvirtide)
Sponsored by Roche and Trimeris
June 16, 2004
Following is the full transcript of The Body's live chat on Fuzeon (T-20, enfuvirtide), which took place on June 16, 2004, at 9 p.m. Eastern Standard Time. The chat was sponsored by Roche and Trimeris, the makers of Fuzeon, moderated by The Body's editorial staff and hosted by Rob, a patient from Los Angeles who is taking Fuzeon, and Don Kurtyka, a nurse practitioner from Florida. This transcript has been edited slightly for grammar and clarity. In rare occurrences, additional follow-up information was obtained from the speakers after the chat's conclusion.
Thank you for joining this interactive Live Chat at TheBody.com! During today's chat, we will be discussing Fuzeon (T-20, enfuvirtide): how it works, how to make injections easier and much more. This chat has been sponsored by Roche/Trimeris, the makers of Fuzeon.
Moderator 1: Thank you all for coming to The Body's live, interactive chat on the HIV medication Fuzeon, also known by the abbreviation T-20 or by its generic name, enfuvirtide.
Moderator 1: Let the chat begin! Please feel free to submit any questions you have for our two speakers: Don Kurtyka, a registered nurse experienced with Fuzeon, and Rob, who is currently taking Fuzeon as part of his HAART regimen.
Moderator 1: Before our two speakers start to answer your questions, though, I'd like to ask them to tell us all a little about who they are and why they're here tonight. Don, would you like to go first?
Reply from Don Kurtyka (Nurse Practitioner): Sure ... I have been involved in HIV care for the last 20 years. I've been a nurse practitioner providing primary HIV and specialty HIV care for the last 12 years in Tampa. I've been working with T-20 and T-1249 for several years, both in clinical studies and since T-20 (Fuzeon) was approved by the FDA [U.S. Food and Drug Administration]. I've lectured at several professional meetings on various topics related to Fuzeon and continue to have patients in various stages of HIV disease on Fuzeon.
Moderator 1: Thank you, Don! How about you, Rob -- what's your story in a nutshell?
Reply from Rob (Patient): Hi, if you didn't get a chance to read my interview, let me say a few words about myself. I was diagnosed HIV+ in 1987. I have had pneumocystis twice -- in 1992 and 1993. The second episode of pneumocystis left me with zero T cells. Since that time I have been on several drug regimens, but it was not until the T-20 that my T cells [rose] to 800 and my viral load [fell] below 50 copies. The reason that I have been asked to join you in the Fuzeon Chat room today is because of my 4 1/2 year experience with Fuzeon (T-20).
To read my complete interview, click on my name in the box to the left of the chat screen.
Moderator 1: Thank you, Rob! I think we're ready to start tackling everybody's questions. Fire away, folks!
Original message from Karen K: Hi Rob! I think it's great that you are here. Can you tell me what it's like to use needles every day? Weren't you scared?
Reply from Rob (Patient): Well, having been HIV+ since 1987, needles are something that I have become very used to. I also had some medical experience in the Navy many years ago so I was not completely unfamiliar with giving injections. Now, after 4 1/2 years, giving myself two daily injections is as easy as taking a pill.
Original message from rick1968: Which other antiretrovirals are best to use in combination with Fuzeon?
Reply from Don Kurtyka (Nurse Practitioner): Rick ... Just about any combination of antiviral agents can be used with Fuzeon. The important thing is to hopefully use at least two other agents that are active, meaning minimal or no resistance to the other agents.
Moderator 1: Our live chat has begun; please continue to submit any questions you may have for Don Kurtyka, a registered nurse experienced with Fuzeon, or Rob, an HIV-positive person currently taking Fuzeon.
Original message from Jim in Illinois: I have been taking Fuzeon for two months now, along with Reyataz [atazanavir] and Norvir [ritonavir], and Viramune [nevirapine]. I had my blood work done last week and [my] viral load is zero and [my T cells] are 600. I am a very thin man, weight is 143 lbs, height is five feet eleven. It is hard for me to find body fat to do the injections. Can you give me any suggestions on that? I have tried not going in too deep with the needle, it seems to make a difference with site reaction. Thanks.
Reply from Rob (Patient): Jim, yes ... I have found that if I put the needle in at a pretty steep angle just under the skin, being careful not to go into muscle tissue, that the ISRs or Injection Site Reactions are minimal, or you may not get any ISRs [at] all. [Rob later amended this response with the following note.] I have also found that you can minimize the ISRs if you massage the injection site right after you have given yourself the injection.
Original message from ptrain: Where does the virus go when Fuzeon prevents it from entering the cell?
Reply from Don Kurtyka (Nurse Practitioner): Interesting question, ptrain! I must admit I've never read or heard anything about this. The virus is blocked from entering the CD4 cell if the Fuzeon is working. Assuming the virus isn't damaged in the process, it would theoretically be circulating with other viral particles in blood, body fluids, etc.
Original message from Karen K: Hi there Rob! Can you tell me how you got used to using needles?
Reply from Rob (Patient): Karen ... The needles really become so easy to use. If you wear contact lenses, you may remember the first time you put them into your eye[s]. It becomes something that you get very used to. Also, if done correctly, you don't even feel the needle when it goes in. Acupuncture is the same type of thing. You can't even feel the needles. I hope this answers your question.
Original message from HIVinvenice: Can you become resistant to T-20?
Reply from Don Kurtyka (Nurse Practitioner): You can definitely become resistant to Fuzeon, just like you could become resistant to other antiviral agents. If someone is on other ACTIVE medications (two or more), the likelihood of developing resistance should be reduced, assuming you take each and every dose of Fuzeon as prescribed. There continues to be a great deal of research being performed related to Fuzeon-related resistance issues.
Original message from GoPistons&Lightningisnottoolong: Hi Rob. Thank you for sharing your experiences with all of us. It is very important for us to hear this. Have you had any side effects from this medicine?
Reply from Rob (Patient): Hey Go Pistons ... The only side effects that I have experienced are the ISRs or Injection Site Reactions. And, if you are careful not to go too deep into muscle tissue, you may have no site reaction at all. The tiny lumps that are the ISRs go away in six or seven days anyway. You do have to be careful not to do your injections too close together; this will cause the ISRs to be larger and more tender. So ... move your injection sites around.
Original message from jbier74866: Can you tell me how to do an injection ... without any body fat? I am very thin.
Reply from Don Kurtyka (Nurse Practitioner): This is one of the most difficult aspects of Fuzeon therapy for very thin people with little fat. Hopefully you have some fat in the typical injection areas: abdomen, thighs, arms. Sometimes it helps to have another person available to help with the injections as they may be able to inject into areas that you might not be able to reach: back of arms, buttocks as a potential site.
Original message from Leo: My question is for Rob. From what I've read, injecting the drug isn't too hard to do by yourself. But preparing each dose sounds complicated. I'm so used to just swallowing pills that I'm worried about how hard the preparation part would be. How long does it take and is it hard to get it right?
Reply from Rob (Patient): I try to mix up my drug about one hour before I give myself the injection. You need to be careful to put the water very slowly into the vial so the powder does not "explode" all over the inside of the vial. Then just wait and eventually the powder will completely dissolve. Then, when you pull the T-20 back into the syringe, do it very slowly so you don't create too many bubbles. You can also mix up two batches together and save one in the refrigerator for later. The mixed T-20 will last, reconstituted, for up to 12 hours.
Original message from Dennis: Don, does [the] use of [a] hot pack diminish the potency of Fuzeon immediately after [an] injection?
Reply from Don Kurtyka (Nurse Practitioner): Dennis: I've never seen any data presented related to this issue. Since we started using Fuzeon, we've encouraged people to try warm packs and/or ice/cold packs to see if they helped reduce ISRs. You bring up an interesting topic ... I don't think that I would stop using hot packs if they work for you.
Original message from lime2004: Rob, how did your physician convince you to go on Fuzeon?
Reply from Rob (Patient): Lime -- That was simple. My T cells were so low and my viral load was so high [that] my doctor just said [he thought] this drug may really work. I was one of the first on the T-20 study. The drug has been amazing for me. My T cells have gone from zero to 800, and my viral load is now undetectable.
Original message from jbier74866: Is it OK to use cortisone cream on the site? And will the hard lumps ever go away?
Reply from Rob (Patient): Don, can you answer this question?
Reply from Don Kurtyka (Nurse Practitioner): Jbier ... The use of hydrocortisone cream[s] and mild steroid creams is common and works for some people in minimizing ISRs or the symptoms they may be causing. There is very little data (again) on this topic. It is very unlikely that this could cause any harm as long as you are using a mild cream (i.e., over-the-counter hydrocortisone 0.5 or 1%).
Original message from Karen K: But Rob, did you use needles before you started Fuzeon? I used drugs for many years and that's how I got infected, so I'm real scared of using needles again.
Reply from Rob (Patient): Karen ... No, I had no personal experience on myself with the use of needles. In the Navy, I gave injections to the troops. You might want to seek the help of a support group for this. I wish I could be more help.
Original message from MDCOZ: Question for Don: Has the drug been used as a first line of treatment yet in those NOT resistant to other meds?
Reply from Don Kurtyka (Nurse Practitioner): Indeed, Fuzeon has been used in first-line treatment. It's not very common in first-line [treatment] for several reasons: expense, most people don't want to deal with injections right away, and there is minimal data from clinical trials to demonstrate any clear reason to do this "up front." It is generally agreed that it's best to use Fuzeon [while] there are still other active drugs to use it with, rather than saving it until someone has resistance to all other drugs, as then it is essentially being used as monotherapy ... definitely not the best use.
Original message from anneRN: Are folks discussing Roche's PAP [Patient Assistance Program] policy? I would like to hear the Roche rep [representative] tackle this one -- I am sure that there are others out there interested in this topic.
Reply from Don Kurtyka (Nurse Practitioner): Anne: I wish I knew if you had a special aspect of concern that you are asking about. I can't speak for Roche, but I would assume they are constantly reviewing their policy. I would suggest giving them a call, visiting their Web site (www.fuzeon.com) or talking with your local rep about your specific questions.
Original message from Dennis: Don, [I] just received phenotyping for all HIV drugs to learn I am resistant to all current drugs. T-20 was not tested. Why? T cell count 4, viral load 500,000 :-(
Reply from Don Kurtyka (Nurse Practitioner): Dennis, resistance testing for Fuzeon is still in its early stages. To the best of my knowledge, only LabCorp (possibly Virco Lab) is offering a Fuzeon panel on their phenotype. I believe Virologic will be offering this soon. The resistance meeting [XIII International HIV Drug Resistance Workshop] in Spain last week had several presentations/posters on Fuzeon resistance, and from what I've read so far we still need to learn more.
Original message from sixtysixer: Rob, have you ever had a problem taking your needles on an airplane?
Reply from Rob (Patient): Sixtysixer ... Actually I just returned from Cancun and when I packed my suitcase I put the needles in the suitcase. I can only imagine the drama that might be caused by someone going through your carry-on and finding the needles. I do carry my pill medication and the T-20 vials in my carry-on because if my suitcase is lost I will at least have the meds. I just cross my fingers and hope that my suitcase arrives when I do. I also carry the used needles back home with me, packed inside my suitcase, so that they can be put into my sharps container.
Original message from smidgeon: How prevalent and disabling are Fuzeon's injection site skin reactions and side effects and also daily whole-body side effects?
Reply from Don Kurtyka (Nurse Practitioner): Fuzeon ISRs are common. In the early clinical trials, over 90% of people developed them, but very few had to discontinue the drug because of them (i.e., they were tolerable, less for some, more for some). There are other side effects that can occur with Fuzeon, but it's important to remember that everybody responds to it (as well as other drugs) differently. If you go to www.fuzeon.com, you will see a link to [info about the] adverse events that have been reported with Fuzeon. The same info should be available on various sites within TheBody.com.
Original message from JakeinChicago: Hi, Don. I was wondering if you could tell me if there are any other fusion inhibitors that are going to be produced any time soon. I heard that there was one being developed that had much less injection site reactions.
Reply from Don Kurtyka (Nurse Practitioner): Jake: There are a number of PIs [protease inhibitors] in clinical development, some that will be out in the next year or so (hopefully). Tipranavir is probably the next one that will hit the market, assuming it is approved by the FDA. It is available in several clinical studies currently. Another one in clinical study is TMC114. You might want to check with your healthcare provider to see what access they have to clinical trials. [Don later amended this response with the following.] There are a number of fusion/entry inhibitors in various stages of clinical trials, including UK-427,857, PRO542, BMS-488043, TAK-799, SCH-C, SCH-D and TNX-355, just to name a few. You may want to check out a couple of Web sites for more details and to find out where these studies are being offered. Try www.amfar.org and www.actis.org.
Original message from fallon_m: Rob -- how do you keep a positive outlook on life? What keeps you going?
Reply from Rob (Patient): Fallon -- I wish I could can it and sell it. It is what keeps me alive and my doctor has confirmed that. Many years ago, he told me I should have been dead a long time ago, and, were it not for my positive attitude, maybe I would be. I look at this disease as an inconvenience. I work with it, not against it. I'm an avid bridge player and I guess I just look at this as the hand that I have been dealt. You have to play your cards the best way you can. Even players dealt good hands can lose. I prefer to take a crappy hand and win with it!
Moderator 1: Just so you all know, this chat will be wrapping up in about 20 minutes. Please continue to submit any questions about Fuzeon that you may have!
Moderator 1: If you've missed any of the chat so far, keep in mind that a full transcript will be available on TheBody.com later this week.
Original message from fallon_m: Does Rob have any other options if Fuzeon stops working? What happens then?
Reply from Rob (Patient): Fallon ... I have not even thought of this scenario. I have been blessed with excellent doctors, doctors [who] have been my partners in the treatment of this disease. Every once in a while my doctor will turn to me and ask how I think he's doing ... like he is my employee. I am flattered by that sort of attitude and it makes me want us both to win. I also look forward to my doctor visits, I guess because I like my doctor so much. Find one that you like and can talk to ... he may become your best friend.
Original message from cyndy88: I have experienced complete treatment failure. I know Fuzeon should be taken with at least two other drugs. I am very resistant to NRTIs and PIs make me very sick. Do you have a suggestion as to particularly effective combinations I can suggest to my doctor when he gets my resistance test?
Reply from Don Kurtyka (Nurse Practitioner): Cyndy: You ask a common question, and a very hard one to answer. I suspect your physician will review your resistance test to see what the best available options are. If you had a phenotype done, s/he might be able to find some agents that, although you are resistant to [them], you may have a low [enough] level of resistance that [they] can be boosted with Norvir. Sometimes we can select other agents that help to keep your replication capacity low ... [there are] lots of ways to work with the current meds to hopefully be able to come up with a regimen that will give you a positive effect. Clinical trials are also another option: There are lots of drugs in development, many of which are being designed to be used [by] people [who] have developed resistance to the current agents.
Original message from reality_bites: Rob: Have you ever missed a dose? How do you make it up?
Reply from Rob (Patient): Reality ... I have missed one dose in 4 1/2 years, and that was because I went on vacation and miscalculated how many I would need. If I am late in taking a dose by, say three or four hours, I try to take my next dose two or three hours later and eventually I get back on my 9 a.m. and 9 p.m. regimen. I have learned not to make myself crazy if I am a bit late. It is not the end of the world. BUT ... I try never to miss a dose.
Original message from Jordon: Don, I know this is not a nice question, but do you know if T-20 interacts with meth?
Reply from Don Kurtyka (Nurse Practitioner): [After the chat, Don clarified and added new details to his original response; the revised version follows.] Jordan: I am not aware of any data related to interactions (or lack of them) between Fuzeon and meth. The obvious response is you shouldn't be using meth at all (but I'm sure you already know that!). Based on drug interaction charts that have been published or posted on the Web, there are likely to be drug-drug interactions between meth and protease inhibitors, and possibly NNRTIs (Sustiva [efavirenz], Viramune [nevirapine]) as well. I would always be concerned about potential interactions when we don't really have an answer.
Moderator 1: Our "Ask the Experts" area, for the record, is located at www.thebody.com/experts.shtml.
Original message from anneRN: My concern with Roche's policy is its stance on "problem payers" -- the title used to describe individuals who have ARV [antiretroviral drug] coverage that does not extend to Fuzeon. With the ADAP [U.S. AIDS Drug Assistance Program] crisis growing by leaps and bounds, Roche has turned its back on the sickest people in the poorest states. I'm sure most of you are aware that people applying to Fuzeon PAP in states where their ADAP is so strapped that caps and restrictions are in place are being denied enrollment in the PAP. In my opinion, this is pharmaceutical blackmail. Without awareness and pressure from consumers, physicians and advocates, I fear this horrible policy will continue.
Reply from Don Kurtyka (Nurse Practitioner): Anne: Thanks for the additional info. We've not experienced the problem you cite, but we have had problems with patients [who] have commercial insurance with an 80/20 copay. They frequently can't pay the 20% and the PAP hasn't been able to help. I don't have an answer, but I can only encourage you to keep talking with the folks at Roche; speak your mind and provide as much information as you can to hopefully change the policy.
Original message from bdgates: Any info on combinations of Fuzeon with Reyataz [ATV, atazanavir] and Emtriva [FTC, emtricitabine]? These would be new drugs to me and I have been exposed to all existing drugs.
Reply from Don Kurtyka (Nurse Practitioner): The important thing is that you take Fuzeon with other active drugs. If Reyataz and Emtriva are believed to be active drugs for you, they should be a good combo with T-20. I am not aware of any specific studies that looked at this specific combination, but there's no reason to suspect it wouldn't be a good regimen!
Moderator 1: Just so you all know, this chat will be wrapping up in about 10 minutes. Please submit any final questions about Fuzeon that you may have!
Original message from bobo407: Why is Fuzeon so painful to inject?
Reply from Rob (Patient): Bobo ... yes. There could be two reasons for this. It's [not] the needle going into the skin but rather still having some of the alcohol on the skin when the needle enters the skin that causes burning. Another thing to be cautious about is having some of the T-20 medication coming out the end of the needle. Before you give yourself the injection you want to bleed off any air in the syringe, but I have learned to then pull just enough air back into the syringe to fill the needle so no medication hits the skin at the injection site. Once you start giving yourself the injections you will find little things that will help. The burning is most probably caused by the alcohol or the T-20 medication at the end of the needle.
Original message from eskimopie: Will they be making Fuzeon into a pill anytime soon?
Reply from Don Kurtyka (Nurse Practitioner): I wish I could answer yes to this one (and so do many patients), but I don't think you'll see Fuzeon in a pill form any time in the near future. The only way Roche was able to manufacture the drug in a stable form was as an injective agent.
Original message from jbier74866: Can you please tell us what our options are as far as injection sites? I didn't realize the buttocks were one. Since mine fell years ago, it would be a good place to use.
Reply from Don Kurtyka (Nurse Practitioner): The buttocks are not recommended as a primary site. If there were not other options, I would consider it (after checking with your personal healthcare provider!).
Original message from HIVinvenice: Does T-20 affect one's sex drive or workout abilities?
Reply from Rob (Patient): HIV ... I have not noticed any change in my sex drive from the T-20. This is not a side effect that I am familiar with. Have you heard something that I haven't?
Moderator 1: Our chat on Fuzeon will be wrapping up in about five minutes. If you have any final questions or comments, now's the time to submit them!
Original message from eskimopie: Rob, how do you keep track of all your meds and when to take them? Any tips?
Reply from Rob (Patient): I prepare my meds for the entire week during the Sunday morning news talk shows. I put the pills into little plastic containers that you can buy at any pharmacy. The plastic boxes are labeled Monday-Sunday and AM, NOON, and PM. It really makes it very simple.
Original message from poz4life: Rob, aside from irritation around the injections, can you tell us of any other major side effects you've had while on Fuzeon?
Reply from Rob (Patient): Poz4life ... actually, I have not experienced any other side effects from using T-20. Again, have you heard anything that I haven't?
Original message from Sam: Do you know if T-1249 is going to still be developed? I heard it was better than T-20.
Reply from Don Kurtyka (Nurse Practitioner): Sam: Roche has discontinued their work on T-1249 according to the last press release that I saw. :(
Original message from Mickey: Hi Don, can you tell me if pregnant women can take this drug? Does it cause birth defects? Have there been a lot of studies on this? My wife needs to take it and we want to have a baby.
Reply from Don Kurtyka (Nurse Practitioner): [After the chat, Don clarified and added new details to his original response; the revised version follows.] There are no adequate or well-controlled studies of Fuzeon in pregnant women, but Fuzeon studies have been done on rats and rabbits (at higher medication dosages than those used in humans) and there was no evidence of harm to the fetus. Based on this, the FDA gave Fuzeon a category B rating. A medication is given category B status if there is no evidence of risk in humans. It could be that either 1) animal findings showed risk, but human studies did not; or 2) no adequate human studies have been done, and animal findings are negative [do not find any problems]. Some of the other antiretroviral medications are in the B class, but most are in the C class, which means that risk cannot be ruled out. In category C, there is a lack of human studies and animal studies are either positive for risk to the fetus or lacking as well. Make sure you talk to your healthcare provider about any plans you have for pregnancy to be sure he/she is comfortable with your drug regimen. [Note from Don Kurtyka, June 24, 2004: U.S. guidelines for the use of HIV medications in pregnant women were revised on June 23. For Fuzeon, the guidelines state that there is "insufficient data to recommend use" of Fuzeon during pregnancy.]
Original message from poz4life: I just want to tell Rob that he is inspiring. I just found out I'm positive in March and it's great to talk to someone who is clearly so well-adjusted.
Reply from Rob (Patient): Poz4life ... you flatter me. I'm not sure I deserve it, but thank you very much. Please, the best advice that I can give is to learn to live with HIV ... don't make it your enemy. Think of it as an inconvenience. Nothing more.
Original message from art: Hi Rob. [My] ISRs are often very sore and kind of swollen, especially in my thighs. Any way to avoid this or alleviate it when it does happen?
Reply from Rob (Patient): Art, try making your injection a bit more shallow. It may cause a little bump under the skin but that's okay. If you are going into muscle, this may be the cause of your reaction. Also, try massaging the injection site right after you pull the needle out.
Original message from Frank: If your doctor doesn't really explain to you about how to do the needles, where can you go to get instruction?
Reply from Don Kurtyka (Nurse Practitioner): Frank: A great question! Hopefully your doctor has a nurse in the office ... s/he should be helpful. Various specialty pharmacies also offer this service. Here in Tampa, Chronimed/Statscript has trainers that can teach self-injection as well as other aspects about HIV and Fuzeon. Often times the local Fuzeon rep knows of experts in the area and can arrange for one of them to visit you in your doctor's office for one-on-one instruction. Hope this helps!
Reply from Rob (Patient): Frank ... your T-20 will come with a complete set of instructions.
[Editor's Note: The following question, though unanswered during the chat itself, was later addressed by Rob; the question and answer are posted immediately below.]
Original message: What's the best way to give myself a Fuzeon injection?
Reply from Rob (Patient): After I have mixed the medication and it is completely dissolved in the vial, I draw the solution back into the syringe very slowly so as not to create too many bubbles or foam. If there are bubbles or foam in the syringe, I just put the syringe down for a few minutes and soon the medication will become a clear liquid. The bubbles and foam will have dissolved into the medication. With the needle pointing upwards, I bleed off any air in the syringe and then -- still with the needle pointing upwards -- I draw back just enough air to fill the needle. This will prevent any medication from dripping out of the end of the needle when you begin to pierce the skin. (Having medication dripping out of the end of the needle is one of the causes of the burning sensation when you give yourself an injection.) Then I aim the needle toward the injection site, being sure the beveled edge of the needle is facing up and the needle is entering the skin [at] a 45 degree angle. From about one inch away from the skin, I move the needle toward the injection site and it easily pierces the skin. I use half-inch, 27 gauge needles. I insert the needle all the way to the hub. Then I gently push the plunger in until all the medication is gone. I pull the needle out quickly and immediately I put my finger on the injection site. I massage the injection site and this decreases the severity of any injection site reaction.
Original message from MagicDoor: Are you going to be doing any other chats in the near future? This has been very helpful! Thank you!
Reply from Rob (Patient): Hey Magic, I would luv to ... all I would need is another invitation.
Original message from HIVinvenice: Thanks for all this time, everyone.
Reply from Rob (Patient): HIV ... you are very welcome. I hope I was able to help.
Reply from Don Kurtyka (Nurse Practitioner): Ditto.
Moderator 1: We'll take one final question before we conclude this chat.
Original message from HIVinvenice: I hate having HIV. Sometimes I wonder if taking all this stuff is worth it. I hope I don't lose it when it comes time to have to start giving myself shots. It would make me feel like I was living by a thread. How do you keep a stiff upper lip?
Reply from Rob (Patient): Well, HIVinvenice, all I have to do is watch world news to realize how fortunate I am to be living the kind of life I am. My HIV, although sometimes [it] has taken me very close to death, has never taken me all the way and I continue to enjoy each day to the fullest. I wish I could give you a real good answer but the bottom line is that I have been born into a place in this world where there ARE medications and there IS hope. So many people in other parts of the world can't say this. I do have hope.
Moderator 1: Our interactive chat on Fuzeon has now concluded. Thank you, Don and Rob, for taking the time to hang out with us (virtually) and answer all these questions!
Reply from Don Kurtyka (Nurse Practitioner): Good night ... this chat was a true pleasure tonight!
Reply from Rob (Patient): Thank you all for joining us today for this chat. I hope we answered some of your questions. It has been a pleasure.
Moderator 1: And a special thank you to everyone who asked questions or took the time to join our chat tonight!
Moderator 1: A full transcript of this chat will be available on TheBody.com later this week.
Moderator 1: To those of you whose questions we were unable to answer tonight: We're sorry we couldn't respond! Please try visiting The Body's Fuzeon page at www.thebody.com/treat/fuzeon.html for more information, or ask our experts at www.thebody.com/experts.shtml.
Moderator 1: You can also visit the official home page for Fuzeon, maintained by the drug's manufacturers Roche and Trimeris, at www.fuzeon.com.
Moderator 1: Thank you all again; have a wonderful night!
Copyright © 2004 Body Health Resources Corporation. All rights reserved.
This article was provided by TheBody.