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An Overview of Truvada (Tenofovir/FTC)

August 23, 2013

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Truvada

Brand Name: Truvada
Other Name(s): FTC/TDF
Drug Class: Nucleoside Reverse Transcriptase Inhibitors
Approved Use: Treatment of HIV Infection; Pre-Exposure Prophylaxis (PrEP) to Reduce the Risk of Sexually Acquired HIV Infection

WARNING:

Truvada can cause serious, life-threatening side effects. These include lactic acidosis (buildup of acid in the blood) and liver problems.

Contact your health care provider right away if you have any of the following symptoms that may signal lactic acidosis:

Contact your health care provider right away if you have any of the following symptoms that may signal liver problems:

Truvada is not approved for the treatment of chronic hepatitis B virus (HBV) infection. Severe worsening of HBV infection has been reported in people co-infected with HBV and HIV who have stopped taking Truvada.

Do not take Truvada to reduce the risk of getting HIV -- also called pre-exposure prophylaxis or PrEP -- unless you are confirmed to be HIV-negative. There is a risk of drug resistance with use of Truvada for PrEP in people with undiagnosed HIV infection.

While taking Truvada, it is important to keep all of your appointments with your health care provider.


What is Truvada?

Truvada is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the following uses:

Truvada contains the following two anti-HIV medicines combined in one pill: emtricitabine and tenofovir disoproxil fumarate. Emtricitabine and tenofovir disoproxil fumarate are types of anti-HIV medicines called nucleoside analog reverse transcriptase inhibitors (NRTIs). NRTIs work by blocking HIV reverse transcriptase, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood.

Truvada does not cure HIV/AIDS. It is not known if Truvada reduces the risk of passing HIV to other people.


What should I tell my health care provider before taking Truvada?

Before taking Truvada, tell your health care provider:

Before taking Truvada to reduce your risk of getting HIV, you must get tested to be sure you are HIV-negative. Do not take Truvada to reduce the risk of getting HIV unless you are confirmed to be HIV-negative.

Before taking Truvada to reduce your risk of getting HIV, tell your health care provider:


How should I take Truvada?

Truvada comes in tablet form. Each tablet contains:

Take Truvada according to your health care provider's instructions.

Take Truvada with or without food at the same time each day.

If you take Truvada to reduce your risk of getting HIV, get tested for HIV at least every 3 months while you are taking Truvada. Always combine use of Truvada with other prevention methods, such as safer sex practices.

If you take too much Truvada, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room right away.

For more information on how to take Truvada, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)


What should I do if I forget a dose?

Take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.


What side effects can Truvada cause?

Truvada can cause serious, life-threatening side effects. These include lactic acidosis (buildup of acid in the blood) and liver problems. (See the WARNING above.)

Other possible side effects of Truvada include:

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Truvada. Ask your health care provider or pharmacist for more information on side effects of Truvada.


How should Truvada be stored?


Where can I find more information about Truvada?

More information about Truvada is available:


Manufacturer Information

Gilead Sciences
800-445-3235




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