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Information

An Overview of Intelence (TMC125, Etravirine)

November 23, 2016

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What Should I Do If I Forget a Dose?

If you miss a dose within 6 hours of the time you usually take it, take your dose after a meal as soon as possible. Then take your next dose at the regularly scheduled time. If you miss a dose by more than 6 hours of the time you usually take it, wait and then take the next dose at the regularly scheduled time. Do not take more than your prescribed dose to make up for a missed dose.


What Side Effects Can Etravirine Cause?

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Etravirine may cause side effects. Most side effects from etravirine are manageable, but a few can be serious. Serious side effects of etravirine include severe skin rash and allergic reactions. (See the WARNING above.)

Other possible side effects of etravirine include:

  • Immune reconstitution inflammatory syndrome (IRIS), a condition that sometimes occurs when the immune system begins to recover after treatment with an HIV medicine. As the immune system gets stronger, it may have an increased response to a previously hidden infection.
  • Changes in body fat (including gain or loss of fat).
  • Tingling, numbness, or pain in your hands or feet (peripheral neuropathy) (in adults).
  • Diarrhea (in children).

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of etravirine. To learn more about possible side effects of etravirine, read the drug label or package insert or talk to your health care provider or pharmacist. 

The AIDSinfo fact sheet on HIV Medicines and Side Effects also includes information that may apply to etravirine.

You can also report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online at www.accessdata.fda.gov/scripts/medwatch/


How Should Etravirine Be Stored?

  • Store etravirine at 59°F to 86°F (15°C to 30°C).
  • Keep etravirine in the container that it came in and keep the container tightly closed. If the container has a small packet of drying agent (called a desiccant), do not remove it. The desiccant protects the medicine from moisture. Do not eat the desiccant packets.
  • Do not use etravirine if the original seal over the container opening is broken or missing.
  • Throw away etravirine that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
  • Keep etravirine and all medicines out of reach of children.


Where Can I Find More Information About Etravirine?

More information about etravirine is available:


Manufacturer Information

Janssen Pharmaceuticals, Inc.
800-526-7736

The above Patient Version drug summary is based on the following FDA label(s): Tablet.

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This article was provided by AIDSinfo. Visit the AIDSinfo website to find out more about their activities and publications.
 

 

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