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An Overview of Rifampin (Rifadin, Rimactane)

October 2, 2012


Brand Name: Rifampin
Other Names: RIF, Rifadin, Rimactane

What is rifampin?

Rifampin is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of tuberculosis (TB). Rifampin is also FDA-approved to treat people who have the bacterium Neisseria meningitidis but have no symptoms. TB is an opportunistic infection. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems -- such as those infected with HIV -- than in people with healthy immune systems.

Rifampin can also be used "off-label" to prevent and treat other opportunistic infections of HIV infection. "Off-label" use refers to use of an FDA-approved medicine in a manner different from that described on the medicine label. Good medical practice and the best interests of a patient sometimes require that a medicine be used "off-label."

What HIV-related opportunistic infections is rifampin used for?

The Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the U.S. Department of Health and Human Services (HHS) and the Centers for Disease Control and Prevention (CDC), includes recommendations on the HIV-related uses of rifampin to treat:

What should I tell my health care provider before taking rifampin?

Before taking rifampin, tell your health care provider:

Ask your health care provider about possible side effects from rifampin. Your health care provider will tell you what to do if you have side effects.

How should I take rifampin?

Take rifampin according to your health care provider's instructions. Your health care provider will tell you how much rifampin to take and when to take it. Before you start rifampin and each time you get a refill, read any printed information that comes with your medicine.

How should rifampin be stored?

Where can I find more information about rifampin?

More information about rifampin is available:

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