Public Health Service Guidelines for the Management of Possible Sexual, Injecting-Drug-Use, or Other Nonoccupational Exposure to HIV, Including Considerations Related to Antiretroviral Therapy
September 25, 1998
In July, 1997, CDC sponsored the External Consultants Meeting on Antiretroviral Therapy for Potential Nonoccupational Exposures to HIV. This meeting brought together scientists, public health experts, clinicians, members of professional associations, representatives from industry, ethicists, and members of affected communities to discuss concerns related to providing antiretroviral agents to persons after nonoccupational HIV exposure. This report reviews the topics raised at the meeting, discusses background information on patient management options, and presents considerations for antiretroviral therapy.
*In this report, a sexual exposure that can place a person at risk for HIV infection is defined as a discrete penetrative sex act (e.g., acts involving the insertion of the penis into the vagina, anus, or mouth) involving vaginal, anal, penile, or oral contact with the sex partner's potentially infectious body fluids, including substances that have been implicated in the transmission of HIV infection (i.e., blood, semen, vaginal secretions, or other body fluids when contaminated with visible blood).
A nonsexual, nonoccupational exposure (excluding perinatal exposures) that can place a person at risk for HIV infection is defined as a percutaneous penetration (e.g., a needlestick, injection, piercing, or cut with a sharp object); contact with mucous membranes; or contact with skin (especially when the involved skin is chapped, abraded, or affected by dermatitis; when the contact is prolonged; or when the involved area is extensive) and substances that have been implicated in the transmission of HIV infection (i.e., blood, tissues, or other body fluids when contaminated with visible blood).
**Information included in these recommendations may not represent Food and Drug Administration approval or approved labeling for the particular products or indications in question. Specifically, the terms "safe" and "effective" may not be synonymous with the FDA-defined legal standards for product approval.
This article was provided by U.S. Centers for Disease Control and Prevention. It is a part of the publication Morbidity and Mortality Weekly Report. Visit the CDC's website to find out more about their activities, publications and services.