| Acute hepatitis C |
Newly acquired symptomatic hepatitis C virus (HCV) infection. |
| ALT |
Alanine aminotransferase. |
| Anti-HCV |
Antibody to HCV that develops in response to
HCV infection; detectable in persons with acute, chronic,
and resolved infection. |
| AST |
Aspartate aminotransferase. |
| Chronic (persistent) HCV infection |
Persistent infection with HCV; characterized by detection of HCV RNA 6 months after newly acquired infection. |
| Chronic hepatitis C |
Liver inflammation in patients with chronic
HCV infection; characterized by abnormal levels of liver enzymes. |
| CSTE |
Council of State and Territorial Epidemiologists. |
| DNA |
Deoxyribonucleic acid. |
| EIA |
Enzyme immunoassay. |
| FDA |
U.S. Food and Drug Administration. |
| HBV |
Hepatitis B virus. |
| HCC |
Hepatocellular carcinoma. |
| HCV |
Hepatitis C virus. |
| HCV-positive |
Positive for anti-HCV as verified by supplemental testing or positive for HCV RNA. |
| HCV RNA |
Hepatitis C virus ribonucleic acid. |
| HIV |
Human immunodeficiency virus. |
| IG |
Immune globulin. |
| IM |
Intramuscular. |
| IV |
Intravenous. |
| MSM |
Men who have sex with men. |
| NHANES III |
Third National Health and Nutrition Examination Survey. |
| NIH |
National Institutes of Health. |
| Positive predictive value |
Probability that a positive screening test is truly positive; dependent on prevalence of disease in a population. |
| Qualitative RT-PCR for HCV RNA |
Test to detect HCV RNA by amplification of
viral genetic sequences. |
| Quantitative assays for HCV RNA |
Tests to detect HCV RNA concentration (viral load)
by amplification of viral genetic sequences or by signal amplification. |
| Resolved HCV infection |
Recovery following hepatitis C virus infection;
characterized by sustained disappearance of serum HCV RNA and normalization of liver enzymes. |
| RIBATM
|
Recombinant immunoblot assay. |
| RNA |
Ribonucleic acid. |
| RT-PCR |
Reverse transcriptase polymerase chain reaction. |
| STD |
Sexually transmitted disease. |
| Supplemental anti-HCV test |
Additional test (i.e.,RIBATM) used to verify a positive anti-HCV result obtained by EIA. |