Warning about Treatment Interruptions
Drug treatment interruptions are risky. For most people, the HIV RNA viral load increases and the CD4 cell count decreases. The decreased CD4 cell count might place many at risk for AIDS-defining, life-threatening OIs. Note that this happened to some study subjects in the STI trial known as the Frankfurt cohort. Another risk is that HIV might be able to seed previously uninfected cells or reseed different types of immune cells and various body compartments. Theoretically, when and if a cure is discovered, this might make HIV eradication in the future more difficult. Do not start a treatment interruption without discussing the issue fully with a physician.
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