Print this page    •   Back to Web version of article

Medical News
Aggressive HIV Strain Appears to Be Isolated Case

July 27, 2005

A presentation Monday at the 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment in Rio de Janeiro refuted the notion of an outbreak of a new, highly aggressive and multiple drug-resistant HIV strain in New York City. On Feb. 11, the New York City Department of Health issued a press release warning of a man infected by such a strain. Reports on the case followed in the medical journal Lancet and elsewhere.

The apparent source for the New York man's HIV infection is a Connecticut man whose clinical course is typical of AIDS patients with his disease, behavior, and medical compliance, reported Dr. Gary Blick, medical and research director of Circle Medical LLC, Norwalk, Conn. "He is not a rapidly progressive patient," said Blick.

The Connecticut patient carries an HIV strain that is a 99.5 percent genetic match to that of the New York patient, said Blick. The Connecticut man's life partner carries an HIV strain that is a 98.5 percent match, and has a similarly unremarkable disease course. The patients involved were able to identify each other visually and confirm they had previously had anal intercourse, said Blick.

The Connecticut patient's virus has a replication capacity of 41 percent, and since he has become treatment compliant, his CD4 levels and viral load have remained stable. In contrast, the New York man's virus showed a viral replication capacity of 136 percent; he was infected for only four months before progressing to AIDS. The New York patient also had a history of unprotected sex and multiple partners, often while using crystal methamphetamine.

Blick hypothesized that the rapid course and drug resistance in the New York patient was due to unusual host factors, including an unusually active sex life and heavy drug use. It could also be possible that the virus strain is less responsive to treatment or a combination of the two factors, he said. In addition, said Blick, the widespread practice of "poz-to-poz" unprotected sex may be riskier than previously assumed.

Back to other news for July 27, 2005

Excerpted from:
Reuters
07.25.2005; Karla Harby




This article was provided by CDC National Prevention Information Network. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update. You can find this article online by typing this address into your Web browser:
http://www.thebody.com/content/art25221.html

General Disclaimer: TheBody.com is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through TheBody.com should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.