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Approved Antiretroviral Drugs

Winter 2005/2006

Generic (Common) NameBrand NameCompanyYear Approved
Protease Inhibitors (PIs)
amprenavirAgeneraseGlaxoSmithKline1999; discontinued 2004
atazanavirReyatazBristol-Myers Squibb2003
fosamprenavirLexiva (U.S.); Telzir (Europe)GlaxoSmithKline2003
indinavirCrixivanMerck1996
lopinavir/ritonavirKaletraAbbott2000; Meltrex formulation 2005
nelfinavirViraceptPfizer1997
ritonavirNorvirAbbott1996
saquinavirInvirase (hard-gel)
Fortovase (soft-gel)
Roche1995
1997; withdrawn 2005
tipranavirAptivusBoehringer Ingelheim2005
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
abacavirZiagenGlaxoSmithKline1998
didanosine (ddI)VidexBristol-Myers Squibb1989; extended release Videx EC 2000
emtricitabine (FTC)EmtrivaGilead2003
lamivudine (3TC)EpivirGlaxoSmithKline1995
stavudine (d4T)ZeritBristol-Myers Squibb1994
zalcitabine (ddC)HividRoche1992; withdrawn 2005
zidovudine (AZT)RetrovirGlaxoSmithKline1987
tenofovir DFVireadGilead2002
NRTI Fixed-Dose Combinations
zidovudine/lamivudineCombivirGlaxoSmithKline1997
zidovudine/lamivudine/abacavirTrizivirGlaxoSmithKline2000
lamivudine/abacavirEpzicom (U.S.); Kivexa (Europe)GlaxoSmithKline2004
tenofovir/emtricitabineTruvadaGilead2004
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
delavirdineRescriptorPfizer1997
efavirenzSustiva (U.S.); Stocrin (elsewhere)Bristol-Myers Squibb1998
nevirapineViramuneBoehringer Ingelheim1996
Entry/Fusion Inhibitors
enfuvirtide (T-20)FuzeonTrimeris2003


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