Association Made Between Alcohol Consumption and Medication Adherence
October 17, 2005
R.S. Braithwhite and colleagues at Yale University conducted a study to determine whether there are temporal and dose-response relationships between alcohol consumption and poor adherence to medication. The researchers conducted telephone interviews with participants in the Veterans Aging Cohort Study, an eight-site observational study of HIV-positive and matched HIV-negative veterans in care, to determine whether alcohol consumption on a particular day was associated with nonadherence to prescribed medications on the same day.
"We used the Time Line Follow Back to measure alcohol consumption and the Time Line Follow Back Modified for Adherence to measure adherence," wrote the researchers. "Individuals were categorized as abstainers (no alcohol in past 30 days), nonbinge drinkers (alcohol within past 30 days but less than or equal to four standard drinks on each day), or binge drinkers (more than or equal to five standard drinks on at least 1 day)."
Among 2,702 respondents, the investigators found 1,582 (56.6 percent) were abstainers, 931 (34.5 percent) were nonbinge drinkers and 239 (8.9 percent) were binge drinkers. Abstainers missed medication doses on 2.4 percent of days surveyed. Nonbinge drinkers missed doses on 3.5 percent of drinking days, 3.1 percent of postdrinking days and 2.1 percent of nondrinking days (p"Binge drinkers missed doses on 11.0 percent of drinking days, 7.0 percent of postdrinking days and 4.1 percent of nondrinking days (pThe study, "A Temporal and Dose-Response Association Between Alcohol Consumption and Medication Adherence Among Veterans in Care," appeared in Alcoholism -- Clinical and Experimental Research (2005;29(7):1190-1197).
This article was provided by CDC National Prevention Information Network. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update.