Is Screening for Sexually Transmitted Infections in Men Who Have Sex With Men Who Receive Non-Occupational HIV Post-Exposure Prophylaxis Worthwhile?
April 13, 2006
Non-occupational HIV post-exposure prophylaxis (NPEP) is routinely prescribed after high-risk sexual exposure. This offers providers the chance to test and treat patients who are at risk of concurrent sexually transmitted infections (STIs). In the current study, researchers set out to assess the efficacy of STI screening in patients undergoing NPEP.
From March 2001 to May 2004, STI screening was offered to all individuals receiving NPEP. The researchers compared the screen results to the type of sexual exposure and baseline patient characteristics.
Eighty-five percent of the target population, 253 men who have sex with men (MSM), were screened. Among the MSM, common exposure risks were receptive anal intercourse (61 percent) and insertive anal intercourse (33 percent). Thirteen percent of subjects, 32 MSM, had one or more STIs. Rectal infections with Chlamydia trachomatis (11 cases; 4.5 percent of MSM) and Neisseria gonorrhoeae (six cases; 2.5 percent of MSM) were most common. Patients with rectal chlamydia were significantly more likely to be co-infected with rectal gonorrhea (p<0.001). The researchers found no association between rectal STI infection and age or exposure risk. Of those individuals with an STI, only six (19 percent) showed symptoms at screening.
"In this cohort of MSM receiving NPEP, high rates of concomitant STIs are observed highlighting the importance of STI screening in this setting," the researchers concluded.
Sexually Transmitted Infections
02.2006; Vol. 82: P. 21-23; E. Hamlyn; J. McAllister; A. Winston; B. Sinclair; J. Amin; A. Carr; D.A. Cooper
This article was provided by CDC National Prevention Information Network. It is a part of the publication CDC HIV/Hepatitis/STD/TB Prevention News Update.