Clinical Trials

• Swedish Medical Center
• University of Washington
• Center for Health Studies, at Group Health Cooperative

Swedish Medical Center

Study #1

The Swedish Research Center is currently studying the safety and efficacy of an investigational formulation of marketed HIV drugs when given in combination with other HIV drugs to people who are HIV positive. To qualify you must be 18 years of age or older, HIV positive, but have not taken anti-HIV medications before.

Qualified participants will receive all study-related care at no cost, including:

• Study medications
• Lab tests
• Physical exams

Reimbursement for childcare and transportation is also available. For more information and/or to find out if you qualify for this study, please contact Janice Price, R.N., at (206) 386-2523.

Study #2

The Swedish Research Center is conducting a clinical research study to test investigational medications for people who are HIV positive. To qualify you must be HIV positive and currently using 3TC and AZT or d4T and have a viral load greater than 400 copies/ml.

Qualified participants will receive all study-related care at no cost, including:

• Study medications
• Lab tests
• Physical exams

Reimbursement for childcare and transportation is also available. For more information and/or to find out if you qualify for this clinical research study, please contact Heather Algren, R.N., at (206) 386-2820.

University of Washington

AIDS Clinical Trials Unit
325 9th Avenue, Second Floor (2 West Clinic)
Seattle WA 98104
206.731.3184
actu@u.washington.edu
http://depts.washington.edu/actu

Latest HIV/AIDS Clinical Trials

Neuropathy Study

Open-Label, Dose-Escalation, Dideoxynucleoside-Associated Distal Symmetric Peripheral Neuropathy Pilot Study

Purpose: to see if taking acetyl-L-carnitine (ALC), an investigational substance, reduces neuropathy (numbness, pain, or tingling in legs and feet) in people who are taking anti-HIV drugs ddC, or ddI or d4T.

Length: 24 weeks

Reimbursement: exams, acetyl-L-carnitine, and lab tests given at no cost. Reimbursement of $20 per visit plus $50 for each visit when skin biopsies are done.

Contact: Alyssa Spingola or Lori Cray at (206) 731-3184 (spingola@u.washington.edu).

Semen Study

Crossover trial of valganciclovir in persons with HIV-1 infection and HIV and CMV co-shedding in semen

Purpose: to evaluate the effectiveness of oral valganciclovir in decreasing the shedding of HIV in semen.

Length: 12 weeks after entry

Reimbursement: Semen samples are reimbursed at the following rates: $15 for screening samples, $25 for each of the three samples at weeks 2-4, and $40 for each of the samples at weeks 8, 10, 11, and 12.

Contact: Leslie Deutsch (206) 543-8299 (leslie@u.washington.edu)

Center for Health Studies, at Group Health Cooperative

Project Plus

Purpose: The Center for Health Studies is now enrolling community participants for a research study to develop an HIV health management program specifically for people aged 50 and older.

To qualify, you must be aged 50 years or older and currently be prescribed antiretroviral medication to treat HIV. Study volunteers do not have to be GHC members.

What does the study involve?

• Complete one 30-40 minute survey interview about your health, medications and attitudes and get $25.
• If you are eligible and interested, we'll ask you to visit the Center for Health Studies Research Clinic for 6 free 60-minute individual or group sessions. Session topics will match your individual interests and could include: treatment information, keeping track of your health and medications, communicating with medical providers, and setting personal health goals.
• Get another $25, if you attend a second 30-40 minute interview and tell us what you liked and didn't like about the individual or group counseling sessions.

For more information about Project Plus, call Christine at (206) 287-2701. The Center for Health Studies is located in downtown Seattle (1730 Minor Avenue).