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CDC Establishes Non-occupational Post-exposure Prevention Registry

April 14, 2000

The CDC (Centers for Disease Control) has established a registry to collect information on the use of non-occupational post-exposure prophylaxis. Post-exposure prevention, also known as PEP, is the use of antiretroviral medications following a known or suspected exposure to HIV to prevent transmission of the virus. PEP has been used for many years in an "occupational" or work-related setting where a medical worker suspected an exposure due to a needle stick or contact with HIV infected body fluids. Recent data from a study being conducted in San Francisco suggests that PEP may be effective in preventing HIV transmission in "non-occupational" settings, situations where there is an unanticipated sexual or drug-related exposure to HIV.

Health care providers are being requested to report all circumstances where PEP is considered, whether it is actually used or not. All reporting is anonymous, and no names or other patient identifying information is being kept. Reporting is not mandatory, but will greatly assist the CDC in evaluating the use of PEP.

The newly established registry will help the CDC collect information on the use of PEP for non-occupational HIV exposures and will gather important utilization, safety, and outcome information about the use of antiretroviral agents (HIV medications) in non-HIV infected people who receive PEP due to a suspected HIV exposure. For information regarding the National Registry for Non-Occupational HIV Post-Exposure Prophylaxis, you may call the registry staff on their toll free number: 1-877-448-1737. You may also visit their Internet website at:

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