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CDC: Surveillance for AIDS-Defining Opportunistic Illnesses, 1992-1997

Table 6

April 19, 1999

TABLE 6. Incidence* of acquired immunodeficiency syndrome-defining opportunistic illnesses, by disease and year of diagnosis -- Adult/Adolescent Spectrum of HIV Disease project,+ 1992-1997

Disease Overall
(N&=22,558)
1992
(N=10,227)
1993
(N=11,261)
1994
(N=10,843)
1995
(N=9,511)
1996
(N=8,046)
1997
(N=5,641)
Trend@
Any OI 273.9 327.2 277.8 304.7 269.2 215.0 147.7 decreasing
Pneumocystis carinii
pneumonia
87.9 108.3 91.9 87.6 94.1 66.7 45.5 decreasing
Mycobacterium avium
complex
76.6 101.4 85.1 78.6 73.0 59.7 15.6 decreasing
Esophageal candidiasis 58.7 61.2 58.3 59.7 60.2 64.6 32.3 none
Cytomegalovirus retinitis 51.2 66.2 58.0 54.1 48.4 35.2 17.4 decreasing
Wasting syndrome 50.0 65.5 51.3 44.1 52.2 40.5 32.0 decreasing
Kaposi sarcoma 45.0 60.6 42.6 50.9 44.4 30.7 19.7 decreasing
HIV encephalopathy 34.8 39.6 38.0 35.4 36.7 27.4 18.6 decreasing
Cytomegalovirus disease 32.3 45.3 29.3 33.6 33.8 23.5 12.8 decreasing
Recurrent pneumonia 20.2 22.0 19.1 25.6 19.3 16.7 10.7 none
Extrapulmonary cryptococcosis 16.3 18.4 17.2 16.4 14.6 16.9 10.4 decreasing
Chronic cryptosporidiosis 14.1 16.4 15.1 17.9 11.4 12.0 3.7 decreasing
Toxoplasmosis of brain 13.7 20.7 15.2 14.7 10.2 8.2 7.0 decreasing
Pulmonary tuberculosis 11.1 16.2 12.1 11.1 9.3 4.3 11.0 decreasing
Chronic herpes simplex 10.3 17.5 12.0 9.8 7.6 5.0 2.8 decreasing
Progressive multifocal
leukoencephalopathy
8.9 9.7 8.2 8.8 10.9 9.5 2.7 none
Extrapulmonary tuberculosis 7.7 11.7 9.5 7.2 6.5 4.5 1.8 decreasing
Immunoblastic lymphoma 6.7 6.2 7.9 6.8 6.4 6.7 4.7 none
Other disseminated
Mycobacterium
6.6 11.2 8.9 4.5 5.2 3.9 2.0 decreasing
Primary brain lymphoma 5.2 6.6 4.5 8.0 4.2 3.5 1.1 none
Disseminated histoplasmosis 3.5 5.0 2.8 4.5 2.1 3.5 1.8 none
Invasive cervical cancer** 3.0 0.0 1.8 9.0 0.5 2.5 2.6 none
Pulmonary candidiasis 2.0 3.5 1.9 2.3 2.0 0.4 0.2 decreasing
Burkitts lymphoma 1.3 0.5 2.7 1.2 1.1 0.3 2.3 none
Disseminated coccidioidomycosis 0.5 0.8 0.2 0.4 0.0 0.6 1.8 none
Chronic isosporiasis 0.2 0.1 0.4 0.0 0.2 0.2 0.0 none
Recurrent Salmonella
septicemia
0.2 0.0 0.4 0.4 0.2 0.1 0.0 none

* Per 1,000 person-years standardized to national acquired immunodeficiency syndrome surveillance cases by age, race, country of birth, sex, human immunodeficiency virus (HIV) exposure mode, and CD4+ T-lymphocyte distribution. Data from all cities are weighted equally.

+ A CDC-sponsored surveillance project that collects data at selected sites in 11 U.S. cities.

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& -- N = number of persons at risk for any AIDS-defining OI; number of persons varies for each disease.

@ -- The direction of change is given for trends that were significant (p<0.05) based on the stratified (CD4+ T-lymphocyte count, HIV exposure mode, race, sex, age, metropolitan area, and country of birth) Cochran-Mantel-Haenszel statistic.

** In a comparison of data in Tables 7 and 8, the difference by sex for this item was significant using the stratified CMH statistic; the percentage was higher for females (p<0.05).


  
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This article was provided by U.S. Centers for Disease Control and Prevention. It is a part of the publication Morbidity and Mortality Weekly Report.
 

 

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