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Selected Primate Models of HIV Infection

January 2000

Virus Viral replication Disease manifestation
Rhesus macaque
  SIVsm PBj14 high <1 yr progression to AIDS
  SHIV KU2 high 1-2 yr progression to AIDS
  SIVmac239 high 2 yr progression to AIDS
  SIVmac251 high 2 yr progression to AIDS
  SHIV 89.6P high 2 yr progression to AIDS
  SIVsmE660 high 3 yr progression to AIDS
  HIV-2 low transient infection
Chimpanzee
  HIV-1 JC high high viremia, rapid CD4 decline
  HIV-1 DH12 high persistent infection; no disease
  HIV-1 5016 high persistent infection; no disease
  HIV-1 LAI med persistent infection; no disease
  HIV-1 SF2 low transient infection


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