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P-gp and the Drugs It Affects

July 2000

Commonly used medications known to be exported out of human cells by the P-glycoprotein:

Cancer Drugs

  • Actinomycin-D

  • Daunorubicin

  • Doxorubicin


  • Paclitaxel

  • Teniposide

  • Vinblastine

  • Vincristine

HIV Drugs (PIs)

  • Amprenavir

  • Indinavir

  • Nelfinavir

  • Ritonavir

  • Saquinavir

Other Affected Drugs

  • Colchicine

  • Domperidone

  • Etoposide

  • Loperamide

  • Ondansetron

  • Rifampicin

  • Rhodamine-123

Cardiac Drugs

  • Digoxin

  • Quinidine


  • Cyclosporin-A

  • FK506

Steroidal Agents

  • Dexamethasone

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This article was provided by Treatment Action Group. It is a part of the publication TAGline.