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The Body Covers: The XIII International AIDS Conference
Hormones and Body Composition

July 12, 2000

  • Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting (Poster, WePpB1383)
    Authored by C. Corcoran

C. Corcoran investigated the independent effects of testosterone and progressive resistance training (PRT) in patients with normal testosterone levels and wasting. Fifty-four eugonadal men with AIDS wasting (<90% ideal body weight (IBW) and/or weight loss >10%) were randomized to receive testosterone (200mg/week or placebo injections) and to progressive resistance training (PRT three times per week or no PRT) for 12 weeks in a factorial study design. Lean body mass (LBM) was assessed by DEXA, cross-sectional muscle area was determined by CT scan, and muscle strength was determined by isometric testing.

The conclusions were that both interventions work, separately, but they work even better when used in combination. Today, HAART has made wasting a much less frequent problem in the developed world. Simple interventions like the ones presented can markedly help patients with this complication. Exercise also improves self esteem and well being, which are additional benefits of that intervention.

See Also
An HIVer's Guide to Metabolic Complications
More Research on HIV/AIDS Wasting

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