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The Body Covers: The 39th Annual Meeting of the Infectious Diseases Society of America
HIV/AIDS: Antiretroviral Therapy (Poster Session 87)

Coverage provided by Douglas T. Dieterich, M.D.

October 27, 2001

A note from TheBody.com: Since this article was written, the HIV pandemic has changed, as has our understanding of HIV/AIDS and its treatment. As a result, parts of this article may be outdated. Please keep this in mind, and be sure to visit other parts of our site for more recent information!

  • Relationship Between Prior Antiretroviral Therapy (ART) and Genotypic Testing (GT) Among a Large Cohort of HIV-1 Isolates (Poster 713)
    Authored by Rafael Campo, German Suarez, Isabella Rosa, Fernando Rivera, Dhuyshantha Jayaweera, Allan Rodriguez, Michael Kolber, Nelson Rodriguez, Roberto Patarca, University of Miami, Miami, FL


This is an interesting perspective on the perplexing problem of resistance. This group looked at the results of genotypic testing done by Visible Genetics and compared it to actual drugs taken. The results showed that protease inhibitor resistance (46%) was less common than NNRTI resistance (77%) in patients failing initial regimens. However, nucleoside analogue resistance was more common in protease failures (85%) than in NNRTI failures (46%). This is a new finding and may influence the sequence of antiretroviral regimens if confirmed by other trials. Lots of questions remain and further analysis of more patients needs to be done before any firm conclusions can be drawn. However, these can be intriguing results.


A note from TheBody.com: Since this article was written, the HIV pandemic has changed, as has our understanding of HIV/AIDS and its treatment. As a result, parts of this article may be outdated. Please keep this in mind, and be sure to visit other parts of our site for more recent information!

See Also
The Body's Guide to HIV Drug Resistance
HIV Mutations



  
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Please note: Knowledge about HIV changes rapidly. Note the date of this summary's publication, and before treating patients or employing any therapies described in these materials, verify all information independently. If you are a patient, please consult a doctor or other medical professional before acting on any of the information presented in this summary. For a complete listing of our most recent conference coverage, click here.

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